Prevalence of Itch in German Schoolchildren: A Population-based Study

Authors

DOI:

https://doi.org/10.2340/actadv.v102.1063

Keywords:

itch, pruritus, epidemiology, quality. of life, prevalence

Abstract

Itch is a common symptom, but there is limited evidence on the prevalence of itch in children. The aim of this study was to assess the prevalence of itch in schoolchildren. A questionnaire was developed by experts in the field and based on a literature search. The questionnaire was applied in a pilot study of 25 consecutively selected paediatric patients and their parents. It confirmed the high content validity of the questionnaire, and the questionnaire was comparable to hospital records regarding chronic itch (n = 19, mean consistency 89.47%). The questionnaire was distributed among German schoolchildren in 9/12 randomly selected primary schools in Kiel, Germany. Of 1,722 invited students, 443 schoolchildren aged 6–10 years participated, and 26.2% (n = 116) reported itch. The prevalence of acute itch was 20.0% (n = 87), and 14.7% (n = 65) reported chronic itch. Reduced sleep and mood were often related to chronic itch. This study demonstrated that itch is a common symptom in German schoolchildren.

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References

Hay RJ, Johns NE, Williams HC, Bolliger IW, Dellavalle RP, Margolis DJ, et al. The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions. J Invest Dermatol 2014; 134: 1527-1534.

https://doi.org/10.1038/jid.2013.446 DOI: https://doi.org/10.1038/jid.2013.446

Ganemo A, Svensson A, Lindberg M, Wahlgren CF. Quality of life in Swedish children with eczema. Acta Derm Venereol 2007; 87: 345-349.

https://doi.org/10.2340/00015555-0245 DOI: https://doi.org/10.2340/00015555-0245

Weisshaar E, Dalgard F. Epidemiology of itch: adding to the burden of skin morbidity. Acta Derm Venereol 2009; 89: 339-350.

https://doi.org/10.2340/00015555-0662 DOI: https://doi.org/10.2340/00015555-0662

Halvorsen JA, Dalgard F, Thoresen M, Bjertness E, Lien L. Itch and mental distress: a cross-sectional study among late adolescents. Acta Derm Venereol 2009; 89: 39-44.

https://doi.org/10.2340/00015555-0554 DOI: https://doi.org/10.2340/00015555-0554

Bylund S, Kobyletzki LB, Svalstedt M, Svensson Å. Prevalence and incidence of atopic dermatitis a systematic review. Acta Derm Venereol 2020; 100: adv00160

https://doi.org/10.2340/00015555-3510 DOI: https://doi.org/10.2340/00015555-3510

Williams HC, Burney PG, Hay RJ, Archer CB, Shipley MJ, Hunter JJ, et al. The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol 1994; 131: 383-396.

https://doi.org/10.1111/j.1365-2133.1994.tb08530.x DOI: https://doi.org/10.1111/j.1365-2133.1994.tb08530.x

von Kobyletzki LB, Berner A, Carlstedt F, Hasselgren M, Bornehag CG, Svensson Å. Validation of a parental questionnaire to identify atopic dermatitis in a population-based sample of children up to 2 years of age. Dermatology 2013; 226: 222-226.

https://doi.org/10.1159/000349983 DOI: https://doi.org/10.1159/000349983

von Kobyletzki LB, Bornehag CG, Breeze E, Larsson M, Lindström CB, Svensson Å. Factors associated with remission of eczema in children: a population-based follow-up study. Acta Derm Venereol 2014; 94: 179-184.

https://doi.org/10.2340/00015555-1681 DOI: https://doi.org/10.2340/00015555-1681

Fang MM, Nowinski CJ, Lai J, Shaunfield S, Silverberg JI, Rangel SM, et al. Characteristics and impacts of itch in children with inflammatory skin disorders. Br J Dermatol 2012; 184: 896-904.

https://doi.org/10.1111/bjd.19541 DOI: https://doi.org/10.1111/bjd.19541

Matterne U, Apfelbacher CJ, Loerbroks A, Schwarzer T, Buttner M, Ofenloch R, et al. Prevalence, correlates and characteristics of chronic pruritus: a population-based cross-sectional study. Acta Derm Venereol 2011; 91: 674-679.

https://doi.org/10.2340/00015555-1159 DOI: https://doi.org/10.2340/00015555-1159

Dalgard FJ, Svensson A, Halvorsen JA, Gieler U, Schut C, Tomas-Aragones L, et al. Itch and mental health in dermatological patients across Europe: a cross-sectional study in 13 countries. J Invest Dermatol 2020; 140: 568-573.

https://doi.org/10.1016/j.jid.2019.05.034 DOI: https://doi.org/10.1016/j.jid.2019.05.034

Matterne U, Strassner T, Apfelbacher CJ, Diepgen TL, Weisshaar E. Measuring the prevalence of chronic itch in the general population: development and validation of a questionnaire for use in large-scale studies. Acta Derm Venereol 2009; 89: 250-256.

https://doi.org/10.2340/00015555-0641 DOI: https://doi.org/10.2340/00015555-0641

Ständer S, Schäfer I, Phan NQ, Blome C, Herberger K, Heigel H, et al. Prevalence of chronic pruritus in Germany: results of a cross-sectional study in a sample working population of 11,730. Dermatology 2010; 221: 229-235.

https://doi.org/10.1159/000319862 DOI: https://doi.org/10.1159/000319862

Weisshaar E, Stander S, Gieler U, Matterne U, Darsow U. Entwicklung eines deutschsprachigen Fragebogens zur Erfassung von chronischem Pruritus (AGP-Fragebogen) Hintergrund und erste Ergebnisse. Hautarzt 2011; 62: 914-927.

https://doi.org/10.1007/s00105-011-2236-4 DOI: https://doi.org/10.1007/s00105-011-2236-4

Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology 1993; 186: 23-31.

https://doi.org/10.1159/000247298 DOI: https://doi.org/10.1159/000247298

Desai NS, Poindexter GB, Monthrope YM, Bendeck SE, Swerlick RA, Chen SC. A pilot quality-of-life instrument for pruritus. J Am Acad Dermatol 2008; 59: 234-244.

https://doi.org/10.1016/j.jaad.2008.04.006 DOI: https://doi.org/10.1016/j.jaad.2008.04.006

Ständer S, Weisshaar E, Mettang T, Szepietowski JC, Carstens E, Ikoma A, et al. Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol 2007; 87: 291-294.

https://doi.org/10.2340/00015555-0305 DOI: https://doi.org/10.2340/00015555-0305

Stander S, Zeidler C, Riepe C, Steinke S, Fritz F, Bruland P, et al. European EADV network on assessment of severity and burden of Pruritus (PruNet): first meeting on outcome tools. J Eur Acad Dermatol Venereol 2016; 30: 1144-1147.

https://doi.org/10.1111/jdv.13296 DOI: https://doi.org/10.1111/jdv.13296

Kong HE, Francois S, Smith S, Spraker M, Lawley LP, Lee G, et al. Pruritus assessment tools for 6 to 7-year-old children: KidsItchyQoL and ItchyQuant. Pediatr Dermatol 2021; 38: 591-601.

https://doi.org/10.1111/pde.14563 DOI: https://doi.org/10.1111/pde.14563

Krause K, Kessler B, Weller K, Veidt J, Chen SC, Martus P, et al. German version of ItchyQoL: validation and initial clinical findings. Acta Derm Venereol 2013; 93: 562-568.

https://doi.org/10.2340/00015555-1544 DOI: https://doi.org/10.2340/00015555-1544

von Kobyletzki LB, Thomas KS, Schmitt J, Chalmers JR, Deckert S, Aoki V, et al. What factors are important to patients when assessing treatment response: an international cross-sectional survey. Acta Derm Venereol 2017; 97: 86-90.

https://doi.org/10.2340/00015555-2480 DOI: https://doi.org/10.2340/00015555-2480

Weisshaar E, Szepietowski JC, Dalgard FJ, Garcovich S, Gieler U, Gimenez-Arnau AM, et al. European S2k guideline on chronic pruritus. Acta Derm Venereol 2019; 99: 469-506.

https://doi.org/10.2340/00015555-3164 DOI: https://doi.org/10.2340/00015555-3164

Fölster-Holst R. Itch management in childhood. Curr Probl Dermatol 2016; 50: 173-191.

https://doi.org/10.1159/000446090 DOI: https://doi.org/10.1159/000446090

Phan NQ, Blome C, Fritz F, Gerss J, Reich A, Ebata T, et al. Assessment of pruritus intensity: prospective study on validity and reliability of the visual analogue scale, numerical rating scale and verbal rating scale in 471 patients with chronic pruritus. Acta Derm Venereol 2012; 92: 502-507.

https://doi.org/10.2340/00015555-1246 DOI: https://doi.org/10.2340/00015555-1246

Silverberg JI, Lei D, Yousaf M, Janmohamed SR, Vakharia PP, Chopra R, et al. Measurement properties of the product of investigator's global assessment and body surface area in children and adults with atopic dermatitis. J Eur Acad Dermatol Venereol 2021; 35: 180-187.

https://doi.org/10.1111/jdv.16846 DOI: https://doi.org/10.1111/jdv.16846

Published

2022-05-19

How to Cite

Theodosiou, G., Nissen, T. ., Weisshaar , . E. ., Plachta-Danielzik, S. ., Augustin, M. ., Ständer, S. ., von Kobyletzki, L. B., & Fölster-Holst, R. . (2022). Prevalence of Itch in German Schoolchildren: A Population-based Study. Acta Dermato-Venereologica, 102, adv00718. https://doi.org/10.2340/actadv.v102.1063