TY - JOUR AU - Seyger, Marieke M.B. AU - Augustin, Matthias AU - Sticherling, Michael AU - Bachhuber, Teresa AU - Fang, Juanzhi AU - Hetherington, James AU - Lucas, James AU - Meakin, Sophie AU - Richardson, Craig AU - Paller, Amy S. PY - 2022/02/28 Y2 - 2024/03/28 TI - Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study JF - Acta Dermato-Venereologica JA - Acta Derm Venereol VL - 102 IS - SE - Articles DO - 10.2340/actadv.v101.981 UR - https://medicaljournalssweden.se/actadv/article/view/981 SP - adv00660 AB - <p class="p1">This study is a retrospective analysis using data collected from the Adelphi Paediatric Psoriasis Disease-Specific Programme cross-sectional survey. Despite being treated for their psoriasis, a substantial proportion of paediatric patients presented with moderate (18.3%) or severe (1.3%) disease at sampling; 42.9% and 92.0% had a body surface area (BSA) of &gt;10%, and 38.8% and 100.0% had a Psoriasis Area Severity Index (PASI) score &gt;10, respectively. Overall, 69.9% of patients had only ever been treated with a topical therapy for their psoriasis. For patients with moderate or severe disease at sampling, 16.3% and 14.4% were currently receiving conventional systemics or biologic therapy, respectively. There is a clinical unmet need in this paediatric population; a considerable percentage of patients still experienced moderate or severe disease and persistent psoriasis symptoms, with numerous body areas affected. A significant proportion of patients were undertreated, which may explain the high burden of disease observed.</p> ER -