Can we diagnose sarcopenia using anterior femoral muscle thickness in patients with cardiovascular disease?

Taira Fukuda; Jun  Yokomachi; Suomi  Yamaguchi; Hiroshi  Yagi; Ikuko  Shibasaki; Yuusuke  Ugata; Masashi  Sakuma; Tomohiro  Yasuda; Shichiro  Abe; Hirotsugu  Fukuda; Hideo  Fujita; Shigeru  Toyoda; Toshiaki  Nakajima

doi:10.2340/jrmcc.v7.12378

Authors

Taira Fukuda Department of Liberal Arts and Sciences, Kanagawa University of Human Services, Yokosuka, Kanagawa, Japan
Jun Yokomachi Department of Cardiovascular Medicine, Dokkyo Medical University and Heart Center, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Suomi Yamaguchi Department of Cardiovascular Medicine, Dokkyo Medical University and Heart Center, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Hiroshi Yagi Department of Cardiovascular Medicine, Dokkyo Medical University and Heart Center, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Ikuko Shibasaki Department of Cardiovascular Surgery, Dokkyo Medical University, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Yuusuke Ugata Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Masashi Sakuma Department of Cardiovascular Medicine, Dokkyo Medical University and Heart Center, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Tomohiro Yasuda School of Nursing, Seirei Christopher University, Hamamatsu, Shizuoka, Japan
Shichiro Abe Department of Cardiovascular Medicine, Dokkyo Medical University and Heart Center, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Hirotsugu Fukuda Department of Cardiovascular Surgery, Dokkyo Medical University, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Hideo Fujita Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Shigeru Toyoda Department of Cardiovascular Medicine, Dokkyo Medical University and Heart Center, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan
Toshiaki Nakajima Department of Cardiovascular Medicine, Dokkyo Medical University and Heart Center, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi, Japan; Department of Medical KAATSU Training, Dokkyo Medical University, Shimotsuga-gun, Tochigi, Japan

DOI:

https://doi.org/10.2340/jrmcc.v7.12378

Keywords:

cardiovascular diseases, sarcopenia, ultrasonography

Abstract

Objective: Making the diagnosis of sarcopenia is not always easy and this is especially true for those with cardiovascular disease. The purpose of this study is to investigate whether it is possible to diagnose sarcopenia by using ultrasound-guided measurements of anterior femoral muscle thickness.

Methods: We investigated the utility of ultrasound-guided measurements of anterior femoral muscle thickness in 1075 hospitalized patients with cardiovascular disease (675 men). As a comparison, sarcopenia was assessed by skeletal muscle mass index using bioelectrical impedance analysis and the Asia Working Group for Sarcopenia criteria.

Results: When the receiver operating characteristic curve using muscle thickness was examined, we found this could be used to make the diagnosis of sarcopenia (men: cutoff value 2.425 cm, area under the curve 0.796; women: cutoff value 1.995 cm, area under the curve 0.746). The prevalence of sarcopenia according to the criteria with skeletal muscle mass index was 34.2% in men and 51.8% in women, while its prevalence according to the cutoff value of muscle thickness was 29.2% in men and 36.7% in women.

Conclusion: Ultrasound-guided measurement of the anterior femoral muscle thickness is a simple and useful method to help make the diagnosis of sarcopenia in patients with cardiovascular disease.

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