Pattern of employment and associated factors in long-term lymphoma survivors 10 years after high-dose chemotherapy with autologous stem cell transplantation

Authors

  • C. E. Kiserud National Advisory Unit for Late Effects After Cancer, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway
  • U-M. Fagerli Department of Oncology, St. Olav’s Hospital, Trondheim, Norway; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
  • K. B. Smeland National Advisory Unit for Late Effects After Cancer, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway
  • Ø. Fluge Department of Oncology, Haukeland University Hospital, Bergen, Norway
  • H. Bersvendsen Department of Oncology, University Hospital of North Norway, Tromsø, Norway
  • S. Kvaløy National Advisory Unit for Late Effects After Cancer, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway
  • H. Holte National Advisory Unit for Late Effects After Cancer, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway
  • A. A. Dahl National Advisory Unit for Late Effects After Cancer, Department of Oncology, Oslo University Hospital, Radiumhospitalet, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway

DOI:

https://doi.org/10.3109/0284186X.2015.1125015

Abstract

Background This study examined employment patterns and associated factors in lymphoma survivors treated with high-dose chemotherapy with autologous stem cell transplantation (HDT-ASCT) from diagnosis to a follow-up survey at a mean of 10 years after HDT-ASCT.

Patients and methods All lymphoma survivors aged ≥18 years at HDT-ASCT in Norway from 1987 to 2008, and alive at the end of 2011 were eligible for this cross-sectional study performed in 2012/2013. Participants completed a mailed questionnaire. Job status was dichotomized as either employed (paid work) or not-employed (disability and retirement pension, on economic support, home-makers, or students).

Results The response rate was 78%, and the sample (N = 312) contained 60% men. Mean age at HDT-ASCT was 44.3 and at survey 54.0 years. At diagnosis 85% of survivors were employed, 77% before and 77% after HDT-ASCT, and 58% at follow-up. Forty seven percent of the survivors were employed at all time points. The not-employed group at survey was significantly older and included significantly more females than the employed group. No significant between-group differences were observed for lymphoma-related variables. Fatigue, mental distress and type D personality were significantly higher among those not-employed, while quality of life was significantly lower compared to the employed group. Older age at survey, being female, work ability and presence of type D personality remained significantly related to being not-employed at survey in the multivariable analysis.

Conclusions Our findings show that not-employed long-term survivors after HDT-ASCT for lymphoma have more comorbidity, cognitive problems and higher levels of anxiety/depression than employed survivors. These factors should be checked and eventually treated in order to improve work ability.

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Published

2016-05-03

How to Cite

Kiserud, C. E., Fagerli, U.-M., Smeland, K. B., Fluge, Ø., Bersvendsen, H., Kvaløy, S., … Dahl, A. A. (2016). Pattern of employment and associated factors in long-term lymphoma survivors 10 years after high-dose chemotherapy with autologous stem cell transplantation. Acta Oncologica, 55(5), 547–553. https://doi.org/10.3109/0284186X.2015.1125015

Issue

Vol. 55 No. 5 (2016): Acta Oncologica

Section

Articles