Results of External Irradiation and Low-Dose-Rate Intraluminal Brachytherapy for Esophageal Cancer

Authors

  • Masanori Someya From the Department of Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan (M. Someya, K. Sakata, H. Nagakura, A. Oouchi, M. Hareyama), Department of Radiology, National Hakodate Hospital, Hokkaido, Japan (A. Saito)
  • Koh-Ichi Sakata From the Department of Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan (M. Someya, K. Sakata, H. Nagakura, A. Oouchi, M. Hareyama), Department of Radiology, National Hakodate Hospital, Hokkaido, Japan (A. Saito)
  • Akio Saito From the Department of Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan (M. Someya, K. Sakata, H. Nagakura, A. Oouchi, M. Hareyama), Department of Radiology, National Hakodate Hospital, Hokkaido, Japan (A. Saito)
  • Hisayasu Nagakura From the Department of Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan (M. Someya, K. Sakata, H. Nagakura, A. Oouchi, M. Hareyama), Department of Radiology, National Hakodate Hospital, Hokkaido, Japan (A. Saito)
  • Atsushi Oouchi From the Department of Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan (M. Someya, K. Sakata, H. Nagakura, A. Oouchi, M. Hareyama), Department of Radiology, National Hakodate Hospital, Hokkaido, Japan (A. Saito)
  • Masato Hareyama From the Department of Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan (M. Someya, K. Sakata, H. Nagakura, A. Oouchi, M. Hareyama), Department of Radiology, National Hakodate Hospital, Hokkaido, Japan (A. Saito)

DOI:

https://doi.org/10.1080/028418602317314082

Abstract

The results of definitive radiotherapy to elucidate the optimal doses of external irradiation (ERT) and low-dose-rate intraluminal brachytherapy (ILBT) were analyzed. Between 1979 and 1998, 100 patients with esophageal cancer were treated with ERT and ILBT. ERT was given at a dose of 40-65 Gy/25-32 fractions and ILBT at 10-24.3 Gy/2-3 fractions. The 5-year actuarial survival rate for all cases was 13%, and that for patients with tumors of 5 cm or less in length was 22.6%, while for patients with tumors longer than 5 cm the rate was 5% (p<0.005). In patients with tumors of 5 cm or less in length, the local control rate of those whose ILBT dose was 20 Gy or more was 83%, and for those with an ILBT dose of less than 20 Gy the control rate was 26.5% (p=0.014). In patients with tumors of 5 cm or less in length, the results of treatment with 60 Gy ERT and 20 Gy ILBT were promising and did not cause severe late complications.

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Published

2002-01-01

How to Cite

Someya, M., Sakata, K.-I., Saito, A., Nagakura, H., Oouchi, A., & Hareyama, M. (2002). Results of External Irradiation and Low-Dose-Rate Intraluminal Brachytherapy for Esophageal Cancer. Acta Oncologica, 41(1), 63–68. https://doi.org/10.1080/028418602317314082

Issue

Vol. 41 No. 1 (2002): Acta Oncologica

Section

Articles