Biological Response to Radiation Therapy

Authors

  • Ingela Turesson Units of Oncology and Biomedical Radiation Sciences, Uppsala University, Uppsala, Sweden
  • Jörgen Carlsson Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Uppsala, Sweden
  • Anders Brahme Medical Radiation Physics, Karolinska Institutet, Stockholm, Sweden
  • Bengt Glimelius Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden
  • Björn Zackrisson Department of Oncology, Umeå University, Umeå, Sweden
  • Bo Stenerlöw Units of Oncology and Biomedical Radiation Sciences, Uppsala University, Uppsala, Sweden

DOI:

https://doi.org/10.1080/02841860310004959

Abstract

In an investigation by the Swedish Cancer Society, the present status, critical issues and future aspects and potentials were described by an expert group for each of nine major areas of radiation therapy research. This article deals with biological response to radiation. Separate sections deal with molecular responses to radiation, the stem cell and clonogenic cell concepts and the importance of cell proliferation, cell and tissue responses to doses above and below 1 Gy, respectively, the potential role of intercellular signalling pathways, the so-called bystander effect and radiation biology-based therapy planning and treatment optimization.

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Published

2003-03-01

How to Cite

Turesson, I., Carlsson, J., Brahme, A., Glimelius, B., Zackrisson, B., & Stenerlöw, B. (2003). Biological Response to Radiation Therapy. Acta Oncologica, 42(2), 92–106. https://doi.org/10.1080/02841860310004959