Cytomegalovirus Colitis--A Severe Complication after Standard Chemotherapy

Authors

  • Thomas Matthes From the Divisions of Haematology (T. Matthes), Infectious Diseases (L. Kaiser), Oncology, Department of Medicine (D. Weber, P.Y. Dietrich), University Hospital Geneva, and the Institute of Clinical Pathology (A.M. Kurt) University Medical Centre, Geneva, Switzerland
  • Laurent Kaiser From the Divisions of Haematology (T. Matthes), Infectious Diseases (L. Kaiser), Oncology, Department of Medicine (D. Weber, P.Y. Dietrich), University Hospital Geneva, and the Institute of Clinical Pathology (A.M. Kurt) University Medical Centre, Geneva, Switzerland
  • Damien Weber From the Divisions of Haematology (T. Matthes), Infectious Diseases (L. Kaiser), Oncology, Department of Medicine (D. Weber, P.Y. Dietrich), University Hospital Geneva, and the Institute of Clinical Pathology (A.M. Kurt) University Medical Centre, Geneva, Switzerland
  • Anne-Marie Kurt From the Divisions of Haematology (T. Matthes), Infectious Diseases (L. Kaiser), Oncology, Department of Medicine (D. Weber, P.Y. Dietrich), University Hospital Geneva, and the Institute of Clinical Pathology (A.M. Kurt) University Medical Centre, Geneva, Switzerland
  • Pierre-Yves Dietrich From the Divisions of Haematology (T. Matthes), Infectious Diseases (L. Kaiser), Oncology, Department of Medicine (D. Weber, P.Y. Dietrich), University Hospital Geneva, and the Institute of Clinical Pathology (A.M. Kurt) University Medical Centre, Geneva, Switzerland

DOI:

https://doi.org/10.1080/028418602321028346

Abstract

We report on a case of cytomegalovirus (CMV) enterocolitis occurring in a 65-year-old patient after a first course of standard chemotherapy for a small cell lung carcinoma (SCLC). Colonic biopsies showed typical inclusion bodies, CMV IgM and IgG antibodies were found in the serum, and polymerase chain reaction for CMV-DNA was positive. Lymphopenia and diminished CD4 T-cell counts were observed. Diarrhoea ceased under ganciclovir treatment, the patient recovered, but died several months later of metastatic lung cancer. Significant immunosuppression leading to severe colitis by CMV infection or reactivation can occur after standard chemotherapy.

Downloads

Download data is not yet available.

Downloads

Published

2002-01-01

How to Cite

Matthes, T., Kaiser, L., Weber, D., Kurt, A.-M., & Dietrich, P.-Y. (2002). Cytomegalovirus Colitis--A Severe Complication after Standard Chemotherapy. Acta Oncologica, 41(7-8), 704–706. https://doi.org/10.1080/028418602321028346

Issue

Vol. 41 No. 7-8 (2002): Acta Oncologica

Section

Articles