Tumour Oxygenation During Fractionated Radiotherapy: Comparison with Size-matched Controls

Authors

  • Georg Stüben Department of Radiotherapy, Universita tsklinikum Essen (G. Stu ben, C. Po ttgen, M. Stuschke, H. Sack), Essen, and the Institute of Physiology and Pathophysiology, University of Mainz (O. Thews), Mainz, Germany
  • Oliver Thews Department of Radiotherapy, Universita tsklinikum Essen (G. Stu ben, C. Po ttgen, M. Stuschke, H. Sack), Essen, and the Institute of Physiology and Pathophysiology, University of Mainz (O. Thews), Mainz, Germany
  • Christoph Pöttgen Department of Radiotherapy, Universita tsklinikum Essen (G. Stu ben, C. Po ttgen, M. Stuschke, H. Sack), Essen, and the Institute of Physiology and Pathophysiology, University of Mainz (O. Thews), Mainz, Germany
  • Martin Stuschke Department of Radiotherapy, Universita tsklinikum Essen (G. Stu ben, C. Po ttgen, M. Stuschke, H. Sack), Essen, and the Institute of Physiology and Pathophysiology, University of Mainz (O. Thews), Mainz, Germany
  • Horst Sack Department of Radiotherapy, Universita tsklinikum Essen (G. Stu ben, C. Po ttgen, M. Stuschke, H. Sack), Essen, and the Institute of Physiology and Pathophysiology, University of Mainz (O. Thews), Mainz, Germany

DOI:

https://doi.org/10.1080/028418699431636

Abstract

The effect of fractionated irradiation on the oxygenation status of experimental tumours was investigated using polarographic assessment of the pO2 distribution. Since an improvement in tumour oxygenation could simply be the result of tumour shrinkage, a comparison of pO2 readings of untreated size-matched control tumours was performed. Irradiation was carried out using 6 fractions of 6 Gy applied within 11 days. A comparison of polarographic pO2 data with size-matched untreated tumours revealed a significant improvement in oxygenation after the irradiation. The median pO2

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Published

1999-01-01

How to Cite

Stüben, G., Thews, O., Pöttgen, C., Stuschke, M., & Sack, H. (1999). Tumour Oxygenation During Fractionated Radiotherapy: Comparison with Size-matched Controls. Acta Oncologica, 38(2), 209–213. https://doi.org/10.1080/028418699431636

Issue

Vol. 38 No. 2 (1999): Acta Oncologica

Section

Articles