Non-Hodgkin's Lymphoma Presenting with Prominent Splenomegaly Clinicopathologic Diversity in Relationship to Immunophenotype
DOI:
https://doi.org/10.3109/02841869709001345Abstract
Splenomegaly is an uncommon presenting feature of non-Hodgkin's lymphoma. This is a study of 16 cases of non-Hodgkin's lymphoma presenting with prominent splenomegaly, which includes ten B-cell lymphomas and six T-cell lymphomas. There were distinct clinical and morphologic differences between these two immunologic types of splenic lymphomas, the B-cell types being predominantly low grade and occurring in older individuals whereas the T-cell lymphomas were predominantly high grade and occurred in adolescents and young adults.