Stereotactic Radiosurgery: The Role of Charged Particles

Authors

  • Richard P. Levy Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California, USA
  • Reinhard W. M. Schulte Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California, USA
  • Jerry D. Slater Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California, USA
  • Dan W. Miller Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California, USA
  • James M. Slater Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California, USA

DOI:

https://doi.org/10.1080/028418699431573

Abstract

Stereotactic radiosurgery using charged-particle beams has been the subject of biomedical research and clinical development for more than 50 years. Charged particles of proton mass or greater manifest unique physical properties that can be used to place a high dose of radiation preferentially within the boundaries of a deeply located intracranial target volume. Since 1954, nearly 10000 patients have been treated using this technique. Treated disorders include pituitary tumors, vascular malformations, primary and metastatic brain tumors, and subfoveal neovascularization. Charged-particle radiosurgery is particularly advantageous for the conformal treatment of large and/or irregularly shaped lesions, or for the treatment of lesions located in front of or adjacent to sensitive brain structures.

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Published

1999-01-01

How to Cite

Levy, R. P., Schulte, R. W. M., Slater, J. D., Miller, D. W., & Slater, J. M. (1999). Stereotactic Radiosurgery: The Role of Charged Particles. Acta Oncologica, 38(2), 165–169. https://doi.org/10.1080/028418699431573