Primary Non-Hodgkin's Lymphoma of the Liver

Authors

  • Lorenzo Memeo From the Dipartimento di Medicina Sperimentale e Patologia, Universita` degli Studi ‘La Sapienza’, Roma
  • Irene Pecorello From the Dipartimento di Medicina Sperimentale e Patologia, Universita` degli Studi ‘La Sapienza’, Roma
  • Antonio Ciardi From the Dipartimento di Medicina Sperimentale e Patologia, Universita` degli Studi ‘La Sapienza’, Roma
  • Elisabetta Aiello From the Dipartimento di Medicina Sperimentale e Patologia, Universita` degli Studi ‘La Sapienza’, Roma
  • Angeloluca De Quarto From the Dipartimento di Medicina Sperimentale e Patologia, Universita` degli Studi ‘La Sapienza’, Roma
  • Ugo Di Tondo From the Dipartimento di Medicina Sperimentale e Patologia, Universita` degli Studi ‘La Sapienza’, Roma

DOI:

https://doi.org/10.1080/028418699431276

Abstract

The clinicopathological features of a rare case of primary non-Hodgkin's hepatic lymphoma (PHL) are described and compared to those of the other 76 cases reported in the world literature. PHL is mainly a disease of Caucasian, middle-aged males and, in approximately half of the reported cases, was associated with other diseases involving depression or chronic stimulation of the immune system. Right upper abdominal and epigastric pain with loss of weight are the most common presenting symptoms. The tumour is usually a single large mass involving both hepatic lobes and is almost invariably composed of lymphocytes reacting with B-cell markers. Most tumours are of intermediate or high grade according to the classification of the Working Formulation for Clinical Usage. No correlation is apparent between gross appearance of PHL (massive or nodular) and grade of severity. Chemotherapy or radiotherapy alone appears to be ineffective, while relatively good results can be obtained with combination modalities.

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Published

1999-01-01

How to Cite

Memeo, L., Pecorello, I., Ciardi, A., Aiello, E., De Quarto, A., & Di Tondo, U. (1999). Primary Non-Hodgkin’s Lymphoma of the Liver. Acta Oncologica, 38(5), 655–658. https://doi.org/10.1080/028418699431276