Single Cell Dna Cytophotometry in Clinical Stage I Malignant Melanoma: Relationship to Prognosis

Authors

  • C. Lindholm DEPARTMENTS OF ONCOLOGY AND PATHOLOGY, UNIVERSITY OF UMEÅ, UMEÅ, SWEDEN
  • P.-Å Hofer DEPARTMENTS OF ONCOLOGY AND PATHOLOGY, UNIVERSITY OF UMEÅ, UMEÅ, SWEDEN
  • H. Jonsson DEPARTMENTS OF ONCOLOGY AND PATHOLOGY, UNIVERSITY OF UMEÅ, UMEÅ, SWEDEN

DOI:

https://doi.org/10.3109/02841869009126535

Keywords:

Malignant melanoma, skin, DNA content, single cell cytophotometry, prognostic factors

Abstract

Histological sections of 50 clinical stage I cutaneous melanomas were analyzed by single cell DNA cytophotometry. Forty-two percent of the melanomas had diploid modal values. Ploidy was not significantly related to the level of invasion, melanoma thickness or prognosis. These results are contradictory to published data from flow cytophotometry which, however, differ inter alia concerning patient materials and follow-up times. Mean nuclear area was in our study significantly correlated to the prognosis.

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Published

1990-01-01

How to Cite

Lindholm, C., Hofer, P.- Å, & Jonsson, H. (1990). Single Cell Dna Cytophotometry in Clinical Stage I Malignant Melanoma: Relationship to Prognosis. Acta Oncologica, 29(2), 147–150. https://doi.org/10.3109/02841869009126535

Issue

Vol. 29 No. 2 (1990): Acta Oncologica

Section

Articles