Familial Macroglobulinemia in a Lebanese Family with Two Sisters Presenting Waldenström's Disease

Authors

  • N. Taleb Department of Hematology and Medical Oncology, Hopital Hotel Dieu de France, Beirut, Lebanon
  • A. Tohme Department of Hematology and Medical Oncology, Hopital Hotel Dieu de France, Beirut, Lebanon
  • D. Abi Jirgiss Department of Hematology and Medical Oncology, Hopital Hotel Dieu de France, Beirut, Lebanon
  • J. Kattan Department of Hematology and Medical Oncology, Hopital Hotel Dieu de France, Beirut, Lebanon
  • E. Salloum Department of Hematology and Medical Oncology, Hopital Hotel Dieu de France, Beirut, Lebanon

DOI:

https://doi.org/10.3109/02841869109092443

Keywords:

Waldenström's disease, familial macroglobulinemia

Abstract

We report a non-consanguineous family with ten children, in which two sisters were found to have Waldenström's disease with light chain IgM monoclonal components. Immunoglobulins were examined in four siblings and revealed high serum IgM concentrations with no monoclonal component. This additional case of familial Waldenström's macroglobulinemia stresses the usefulness of screening family members of patients with monoclonal gammopathy since they may be at high risk of developing the disease.

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Author Biography

N. Taleb, Department of Hematology and Medical Oncology, Hopital Hotel Dieu de France, Beirut, Lebanon

 

 

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Published

1991-01-01

How to Cite

Taleb, N., Tohme, A., Abi Jirgiss, D., Kattan, J., & Salloum, E. (1991). Familial Macroglobulinemia in a Lebanese Family with Two Sisters Presenting Waldenström’s Disease. Acta Oncologica, 30(6), 703–705. https://doi.org/10.3109/02841869109092443