Tolerance of Canine Portal Vein Anastomosis to Intraoperative X-Irradiation

Authors

  • K. Ohara Department Of Radiology And Department Of Surgery, Institute Of Clinical Medicine, University Of Tsukuba, Sakura-Mura, Niihari-Gun, Ibaraki, 305, Japan
  • T. Takeshima Department Of Radiology And Department Of Surgery, Institute Of Clinical Medicine, University Of Tsukuba, Sakura-Mura, Niihari-Gun, Ibaraki, 305, Japan

DOI:

https://doi.org/10.3109/02841868709113718

Keywords:

Therapeutic radiology, experimental, dogs, intraoperative x-irradiation, portal vein anastomosis, tolerance

Abstract

Tolerance of surgical portal vein anastomosis to intraoperative radiation therapy (IORT) was studied in dogs after single doses of zero, 10, 20 and 40 Gy (290 kVp x-rays). Portal venography was performed prior to IORT and before sacrificing. The dogs were sacrificed 3 and 12 months respectively after irradiation. Portal venography revealed no radiation induced anastomotic stenosis. Autopsy disclosed macroscopic periportal fibrosis in all dogs, independent of radiation dose and observation periods. Microscopically, the three tunicas of the vein did not show any pathological changes after any dose level.

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Published

1987-01-01

How to Cite

Ohara, K., & Takeshima, T. (1987). Tolerance of Canine Portal Vein Anastomosis to Intraoperative X-Irradiation. Acta Oncologica, 26(6), 459–462. https://doi.org/10.3109/02841868709113718

Issue

Vol. 26 No. 6 (1987): Acta Oncologica

Section

Articles