From recommendation to requirement: why multidisciplinary governance and centralization must become global standards in penile cancer care

Authors

  • Matthias May St. Elisabeth Hospital Straubing, Brothers of Mercy Hospital, Straubing, Germany
  • Christian Gilfrich St. Elisabeth Hospital Straubing, Brothers of Mercy Hospital, Straubing, Germany
  • Ingmar Wolff Department of Urology, University Medicine Greifswald, Greifswald, Germany
  • Steffen Lebentrau Department of Urology, Werner Forssmann Hospital, Eberswalde, Germany; Department of Urology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany

DOI:

https://doi.org/10.2340/sju.v61.45436

Keywords:

Penile squamous cell carcinoma, multidisciplinary tumor boards, centralization of care, volume-outcome relationship, guideline harmonization, quality indicators

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References

Gerdtsson A, Abedi E, Baseckas G, et al. The Swedish national guidelines on penile cancer. Scand J Urol. 2025;60:189–194. https://doi.org/10.2340/sju.v60.44463 DOI: https://doi.org/10.2340/sju.v60.44463

Lebentrau S, May M. Centralization or individualization in penile cancer care: evidence, international insights, and a future framework for Germany. Urologie. 2025;64(12):1297–1306. https://doi.org/10.1007/s00120-025-02721-3 DOI: https://doi.org/10.1007/s00120-025-02721-3

Leitlinienprogramm Onkologie (German Cancer Society, German Cancer Aid, Association of the Scientific Medical Societies in Germany). S3 guideline for the diagnosis, treatment, and follow-up of penile cancer. Long version 1.0. AWMF Registry No. 043-042OL. Berlin; 2020. https://register.awmf.org/de/leitlinien/detail/043-042OL (accessed 30 January 2026)

EAU-ASCO Collaborative Guidelines on Penile Cancer. Presented at the EAU Annual Congress, Madrid, 2025. European Association of Urology Guidelines Office, Arnhem, The Netherlands.

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: penile cancer. Version 1.2026. Plymouth Meeting, PA; 2025. https://www.nccn.org/professionals/physician_gls/pdf/penile.pdf (accessed 30 January 2026)

May M, Lebentrau S, Ayres B, et al. The goal of achieving high-quality surgical first-line therapy in patients with penile cancer is important; However, some collective efforts are still required in order to reach it. Comment on Brassetti et al. combined reporting of surgical quality and cancer control after surgical treatment for penile tumors with inguinal lymph node dissection: the Tetrafecta achievement. Curr Oncol. 2023, 30, 1882–1892. Curr Oncol. 2023;30(4):4269–4274. https://doi.org/10.3390/curroncol30040325 DOI: https://doi.org/10.3390/curroncol30040325

May M, Lebentrau S, Watkin N, et al. Initial presentation of the Pentafecta score as a quality instrument for outcome evaluation of primary surgical treatment in patients with penile cancer. Aktuelle Urol. 2023;54(4):292–298. https://doi.org/10.1055/a-2065-8256 DOI: https://doi.org/10.1055/a-2065-8256

Lebentrau S, Wakileh GA, Schostak M, et al. Does the identification of a minimum number of cases correlate with better adherence to international guidelines regarding the treatment of penile cancer? Survey results of the European PROspective Penile Cancer Study (E-PROPS). Front Oncol. 2021;11:759362. https://doi.org/10.3389/fonc.2021.759362 DOI: https://doi.org/10.3389/fonc.2021.759362

Boehm WU, Piontek D, Latarius S, et al. The clinical complexity of penile cancer: current clinical-epidemiological data from the database of the Free State of Saxony/Germany. Urol Int. 2022;106(7):706–715. https://doi.org/10.1159/000519210 DOI: https://doi.org/10.1159/000519210

Yakac A, Lebentrau S, Lusuardi L, et al. Centralizing penile cancer care in Germany and Austria: just a dream or a fast-approaching reality? Results of a survey study among urological department chairs and modeling of real treatment numbers of penile cancer patients. Urol Int. 2023;107(10–12):916–923. https://doi.org/10.1159/000534089 DOI: https://doi.org/10.1159/000534089

Published

2026-02-10

How to Cite

May, M., Gilfrich, C., Wolff, I., & Lebentrau, S. (2026). From recommendation to requirement: why multidisciplinary governance and centralization must become global standards in penile cancer care. Scandinavian Journal of Urology, 61(1), 29–30. https://doi.org/10.2340/sju.v61.45436

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