A Modified Nottingham Prognostic Index for Breast Cancer Patients Diagnosed in Denmark 1978–1994

Authors

  • Klaus Rostgaard From the University of Copenhagen, Denmark
  • Henning T. Mouridsen Copenhagen University Hospital H:S, Denmark
  • Michael Væth Arhus University, Denmark
  • Helle Holst Technical University of Denmark, Denmark
  • Knud P. Olesen Bispebjerg Hospital H:S, Denmark
  • Elsebeth Lynge From the University of Copenhagen, Denmark

DOI:

https://doi.org/10.1080/02841860152703463

Abstract

Stage of disease at diagnosis is a predictor of breast cancer survival. We used data from the Danish Cancer Register and the Danish Breast Cancer Cooperative Group to study stage distribution in 0–69-year-old Danish breast cancer patients diagnosed in 1978–1994. We constructed a modified Nottingham Prognostic Index (NPI) calculated from the number of excised and positive lymph nodes, malignancy grade and tumour diameter. This NPI could be calculated for 63% of the patients, and among these the stage distribution improved during the study period. The proportion of patients with a poor prognostic score decreased from 27% to 20%. Based on a comparison of the crude 3-year survival of patients with an NPI score and those without, it seems probable that the stage of disease at diagnosis on average improved in Danish breast cancer patients below age 70 during the 1980s and the early 1990s.

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Published

2001-01-01

How to Cite

Rostgaard, K., Mouridsen, H. T., Væth, M., Holst, H., Olesen, K. P., & Lynge, E. (2001). A Modified Nottingham Prognostic Index for Breast Cancer Patients Diagnosed in Denmark 1978–1994. Acta Oncologica, 40(7), 838–843. https://doi.org/10.1080/02841860152703463

Issue

Vol. 40 No. 7 (2001): Acta Oncologica

Section

Articles