The role of personality in the course of health-related quality of life and disease-specific health status among colorectal cancer survivors: A prospective population-based study from the PROFILES registry

Authors

  • Olga usson CoRPS – Center of Research on Psychology in Somatic diseases, Department of Medical and clinical Psychology, Tilburg University, the Netherlands
  • Pauline A. J. Vissers CoRPS – Center of Research on Psychology in Somatic diseases, Department of Medical and clinical Psychology, Tilburg University, the Netherlands; Comprehensive Cancer Centre the Netherlands – Eindhoven Cancer Registry, Eindhoven, the Netherlands
  • Johan Denollet CoRPS – Center of Research on Psychology in Somatic diseases, Department of Medical and clinical Psychology, Tilburg University, the Netherlands
  • Floortje Mols CoRPS – Center of Research on Psychology in Somatic diseases, Department of Medical and clinical Psychology, Tilburg University, the Netherlands; Comprehensive Cancer Centre the Netherlands – Eindhoven Cancer Registry, Eindhoven, the Netherlands

DOI:

https://doi.org/10.3109/0284186X.2014.996663

Abstract

Background. Prospective studies in various cardiovascular populations show that Type D personality predicted impaired health-related quality of life (HRQoL) and disease-specific health status. We examined the effect of negative affectivity (NA), social inhibition (SI) and their combined effect (Type D personality) on HRQoL and disease-specific health status among colorectal cancer (CRC) patients.

Methods. CRC patients diagnosed between 2000 and 2009, as registered in the Dutch population-based Eindhoven Cancer Registry, received questionnaires on Type D personality (DS14), HRQoL (EORTC QLQ-C30) and disease-specific health status (EORTC QLQ-CR38) in 2010, 2011 and 2012.

Results. Response rates were 73% (n = 2625), 83% (n = 1643) and 82% (n = 1458), respectively. Analyses were done on those completing at least two questionnaires (n = 1735). Individuals with Type D (NA+/SI+; 19%) and high NA (NA+/SI-; 11%) reported a significantly worse HRQoL and disease-specific health status compared to NA-/SI+ and NA-/SI-. Differences were stable over time. Linear mixed effects models showed that Type Ds had a lower quality of life, cognitive and emotional functioning, more insomnia, diarrhea, gastrointestinal, defecation and stoma-related problems and poor body image and future perspective compared to the reference group (NA-/SI-), even after controlling for sociodemographic and clinical variables. High NA individuals (NA+/SI-) reported similar poor health outcomes as Type Ds. However, they also reported lower social functioning and more fatigue, pain, micturition- and financial problems, while Type Ds reported more constipation, sexual problems and less sexual enjoyment.

Conclusions. Type D personality and high NA both have a significant negative stable impact on HRQoL and disease-specific health status among CRC patients.

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Published

2015-05-28

How to Cite

usson, O. ., Vissers, P. A. J., Denollet, J., & Mols, F. (2015). The role of personality in the course of health-related quality of life and disease-specific health status among colorectal cancer survivors: A prospective population-based study from the PROFILES registry. Acta Oncologica, 54(5), 669–677. https://doi.org/10.3109/0284186X.2014.996663

Issue

Vol. 54 No. 5 (2015): Acta Oncologica

Section

Articles