Syndecan-1 (CD138) Expression in Acute Myeloblastic Leukemia Cells

Authors

  • Aysel Seftalioglu Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Sema Karakus Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Semra Dundar Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Belgin Can Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Esra Erdemli Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • M. Kemal Irmak Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Emin Oztas Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Cem Korkmaz Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Fatih Yazar Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa
  • Ilkin Cavusoglu Departments of Histology & Embryology, Faculty of Medicine Hacettepe University, Uludag University Bursa

DOI:

https://doi.org/10.1080/0891060310002267

Abstract

Syndecan-1 (CD138), an important transmembrane heparan sulfate proteoglycan is expressed in distinct stages of cell differentiation. Although its expression in acute lymphoblastic leukemia (ALL) cells is well known; its function or presence in acute myeloblastic leukemia (AML) cells is still largely unknown. The expression of syndecan-1 was studied in bone marrow biopsies of three patients with AML using electron microscopic immunocytochemistry. Positive expression of syndecan-1 was found in AML cells. These results suggest that syndecan-1 expression is not only a characteristic phenotypic marker for ALL, but is also expressed in AML cells

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Published

2003-01-01

How to Cite

Seftalioglu, A. ., Karakus, S. ., Dundar, S. ., Can, B. ., Erdemli, E. ., Irmak, M. K. ., … Cavusoglu, I. . (2003). Syndecan-1 (CD138) Expression in Acute Myeloblastic Leukemia Cells. Acta Oncologica, 42(1), 71–74. https://doi.org/10.1080/0891060310002267

Issue

Vol. 42 No. 1 (2003): Acta Oncologica

Section

Articles