The potential of proton beam radiation therapy in intracranial and ocular tumours

Abstract

A group of oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy. The estimations have been based on current statistics of tumour incidence, number of patients potentially eligible for radiation treatment, scientific support from clinical trials and model dose planning studies and knowledge of the dose-response relations of different tumours and normal tissues. In intracranial benign and malignant tumours, it is estimated that between 130 and 180 patients each year are candidates for proton beam therapy. Of these, between 50 and 75 patients have malignant glioma, 30–40 meningeoma, 20–25 arteriovenous malformations, 20–25 skull base tumours and 10–15 pituitary adenoma. In addition, 15 patients with ocular melanoma are candidates.