Ki-67 Index in Fine Needle Aspiration Cytology Specimens from Primary and Recurrent Rectal Cancer

Authors

  • Johan N. Wiig Department of Surgical Oncology, The Norwegian Radium Hospital, Oslo, Norway
  • Rune Lilleng The Clinical Cytologie Laboratory of Department of Pathology The Norwegian Radium Hospital, Oslo, Norway
  • Nadir Paksoy The Clinical Cytologie Laboratory of Department of Pathology The Norwegian Radium Hospital, Oslo, Norway
  • Aasmund Berner The Clinical Cytologie Laboratory of Department of Pathology The Norwegian Radium Hospital, Oslo, Norway
  • Saiyinthie Yogesan The Clinical Cytologie Laboratory of Department of Pathology The Norwegian Radium Hospital, Oslo, Norway
  • Karl-Erik Giercksky Department of Surgical Oncology, The Norwegian Radium Hospital, Oslo, Norway

DOI:

https://doi.org/10.3109/02841869609098529

Abstract

A Ki-67 index was determined in 63 fine needle aspiration cytology (FNAC) specimens from patients with rectal cancer, 21 with primary cancers and 42 with local recurrences. Seventeen of the patients had received external irradiation before the examination. In primary cancers, in recurrences as well as in the post-irradiation cases, the mean percentage of Ki-67 positive cells was about 55% with a wide variation. The percentage of Ki-67 positive cells was independent of the length of the recurrence-free period. In conclusion, the Ki-67 antigen may well be studied in FNAC specimens. The presence of antigen did not correlate with development of recurrence, length of recurrence-free period or irradiation prior to the analysis.

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Published

1996-01-01

How to Cite

Wiig, J. N. ., Lilleng, R. ., Paksoy, N. ., Berner, A. ., Yogesan, S. ., & Giercksky, K.-E. . (1996). Ki-67 Index in Fine Needle Aspiration Cytology Specimens from Primary and Recurrent Rectal Cancer. Acta Oncologica, 35(Supp 8), 119–121. https://doi.org/10.3109/02841869609098529

Issue

Vol. 35 No. Supp 8 (1996): Acta Oncologica

Section

Articles