Alterations in Head and Neck Cancer Occurring in HIV-infected Patients: Results of a Pilot, Longitudinal, Prospective Study

Authors

  • Bhuvanesh Singh From the Department of Otolaryngology, State University of New York- Health Science Center at Brooklyn, Brooklyn, New York, USA
  • Steven Sabin From the Department of Otolaryngology, State University of New York- Health Science Center at Brooklyn, Brooklyn, New York, USA
  • Omid Rofim From the Department of Otolaryngology, State University of New York- Health Science Center at Brooklyn, Brooklyn, New York, USA
  • Ashok Shaha From the Department of Otolaryngology, State University of New York- Health Science Center at Brooklyn, Brooklyn, New York, USA
  • Gady Har-El From the Department of Otolaryngology, State University of New York- Health Science Center at Brooklyn, Brooklyn, New York, USA
  • Frank E. Lucente From the Department of Otolaryngology, State University of New York- Health Science Center at Brooklyn, Brooklyn, New York, USA

DOI:

https://doi.org/10.1080/028418699432347

Abstract

To assess the impact of human immunodeficiency virus (HIV) infection on the presentation and course of head and neck squamous cell carcinoma (HNSCC), we performed a pilot, prospective, longitudinal study of all patients with HNSCC presenting to our institutions over a 6-month period (n=10). A 60% incidence of HIV infection was seen in this study population, with SCC presenting as the initial manifestation of HIV infection in 2 of the 6 patients. In addition, HIV-infected patients were significantly younger than non-infected patients at (p=0.01). None of the HIV-infected patients had acquired immunodeficiency syndrome (AIDS) at the time of presentation, but 5 of 6 patients had an abnormal CD4 count, compared to none of the non-infected patients (p

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Published

1999-01-01

How to Cite

Singh, B., Sabin, S., Rofim, O., Shaha, A., Har-El, G., & Lucente, F. E. (1999). Alterations in Head and Neck Cancer Occurring in HIV-infected Patients: Results of a Pilot, Longitudinal, Prospective Study. Acta Oncologica, 38(8), 1047–1050. https://doi.org/10.1080/028418699432347