Radiotherapy Alone for Non-Small Cell Lung Carcinoma Five-year disease-free survival and patterns of failure

Authors

  • Michael Koukourakis Department of Radiotherapy and Oncology, Hellenic Cancer Institute. Saint Savvas Hospital, Athens; Department of Radiotherapy and Oncology, University Hospital of Iraklion, Iraklion, Crete, Greece
  • John Skarlatos Department of Radiotherapy and Oncology, Hellenic Cancer Institute. Saint Savvas Hospital, Athens
  • Lambrini Kosma Department of Radiotherapy and Oncology, Hellenic Cancer Institute. Saint Savvas Hospital, Athens
  • Alexandra Giatromanolaki Department of Radiotherapy and Oncology, University Hospital of Iraklion, Iraklion, Crete, Greece
  • Dimitrios Yannakakis Department of Radiotherapy and Oncology, Hellenic Cancer Institute. Saint Savvas Hospital, Athens

DOI:

https://doi.org/10.3109/02841869509094018

Abstract

One hundred and fifty-three patients with inoperable non-small cell lung cancer (NSCLC) treated with radiotherapy alone have been retrospectively analysed. Normalized Total Dose (NTD) as defined by Macejewski, TN-stage (AJC-system) and histology have been examined with respect to 5-year disease-free survival (DFS) and the patterns of failure so as to identify subgroups of patients that routinely should be treated with radical intent. The 5-year DFS for T1, 2-N0, 1 and T3-N0, 1 staged patients was 30% (7/23) and 25% (4/16) respectively when the tumor NTD (a/b = 10 Gy) was 56–64 Gy vs. 12% (5/41) and 0% (0/10) when the NT

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Published

1995-01-01

How to Cite

Koukourakis, M., Skarlatos, J., Kosma, L., Giatromanolaki, A., & Yannakakis, D. (1995). Radiotherapy Alone for Non-Small Cell Lung Carcinoma Five-year disease-free survival and patterns of failure. Acta Oncologica, 34(4), 525–530. https://doi.org/10.3109/02841869509094018

Issue

Vol. 34 No. 4 (1995): Acta Oncologica

Section

Articles