Radioimmunodetection of Ovarian Cancer

Authors

  • Katrine Riklund åhlström Departments of Diagnostic Radiology, University of Umeå, Umeå, Sweden
  • Sven-Ola Hietala Departments of Diagnostic Radiology, University of Umeå, Umeå, Sweden
  • Ulf Stendahl Departments of Gynaecologic Oncology, University of Umeå, Umeå, Sweden
  • Torgny Stigbrand Departments of Medical Biochemistry and Biophysics, University of Umeå, Umeå, Sweden

DOI:

https://doi.org/10.3109/02841869309096128

Abstract

Radioimmunoscintigraphy (RIS) is a potentially valuable method for the detection of primary, secondary and recurrent malignant tumours. Antigens that have been used for monitoring as well as for RIS of ovarian carcinomas include CA 125, PLAP, HMFG, and CA 19–9. Between 70 and 100% of the tumours have been detected at RIS when these antigens have been used. Conventional methods, e.g., computerized tomography (CT) and ultrasonography (US), demonstrate similar or lower detection rate than RIS for tumour diagnosis. RIS gives additional information to conventional radiological methods (CT and US) for the detection of occult ovarian carcinomas. A review of earlier investigations is given and our own recent results using PLAP as a target antigen are presented. The future potential of the technology is discussed.

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Published

1993-01-01

How to Cite

Riklund åhlström, K. ., Hietala, S.-O. ., Stendahl, U. ., & Stigbrand, T. . (1993). Radioimmunodetection of Ovarian Cancer. Acta Oncologica, 32(7-8), 729–734. https://doi.org/10.3109/02841869309096128

Issue

Vol. 32 No. 7-8 (1993): Acta Oncologica

Section

Articles