Prognosis of Breast Cancer with Small Primary Tumor (Pt1)

Authors

  • H. Joensuu Department OF RADIOTHERAPY AND ONCOLOGY, TURKU UNIVERSITY CENTRAL HOSPITAL, TURKU, FINLAND; DEPARTMENT OF PATHOLOGY, UNIVERSITY OF TURKU, TURKU, FINLAND
  • S. Toikkanen Department OF RADIOTHERAPY AND ONCOLOGY, TURKU UNIVERSITY CENTRAL HOSPITAL, TURKU, FINLAND; DEPARTMENT OF PATHOLOGY, UNIVERSITY OF TURKU, TURKU, FINLAND

DOI:

https://doi.org/10.3109/02841869109091822

Keywords:

Breast cancer, prognosis, tumor size, mitotic count, tumor necrosis, histological grade, S-phase fraction, flow cytometry

Abstract

Prognosis of 141 women with pT1 breast cancer from a defined urban area was investigated. Only one of the 47 women with a primary tumor diameter ≤10mm in diameter (pT1a or pT1b) died from breast cancer within 5 years after the diagnosis. The 5-year survival rate corrected for intercurrent deaths of the women with pT1c cancer (from 11 to 20 mm in diameter, n = 94) was 83%; 96% in pT1cNO and 62% in pT1cN+ cancer respectively (p < 0.0001). In a multivariate analysis axillary nodal status and S-phase fraction determined by flow cytometry were independent prognostic factors. The excellent survival of women with pT1a or pT1b breast cancer, and women with pT1cNO breast cancer with no axillary nodal metastases, does not support the policy of giving adjuvant treatment to all women with breast cancer.

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Published

1991-01-01

How to Cite

Joensuu, H., & Toikkanen, S. (1991). Prognosis of Breast Cancer with Small Primary Tumor (Pt1). Acta Oncologica, 30(7), 793–796. https://doi.org/10.3109/02841869109091822

Issue

Vol. 30 No. 7 (1991): Acta Oncologica

Section

Articles