Prognostic Factors in Head and Neck Non-Hodgkin's Lymphoma with Special Reference to Serum Lactic Dehydrogenase and Serum Copper

Authors

  • S. Hisamitsu Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan
  • H. Shibuya Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan
  • M. Hoshina Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan
  • J. Horiuchi Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan

DOI:

https://doi.org/10.3109/02841869009096383

Keywords:

Non-Hodgkin’s lymphoma, head and neck, prog- nostic factors, serum LDH, serum copper

Abstract

An analysis of prognostic variables was performed in a retrospective study of 121 patients with Ann Arbor stage I–II head and neck non-Hodgkin's lymphoma admitted from 1973 to 1988. The overall actuarial 5-year survival rate was 58.8% and the minimum follow-up 15 months. Nine clinical and laboratory parameters were studied, including serum lactic dehydrogenase (LDH) and serum copper (SCL), and subjected to univariate and multivariate analyses. In univariate analysis, histology and LDH were found to be significant prognostic variables. Evaluation by Cox's multivariate proportional hazard model revealed histology, SCL and sex to be of prognostic significance.

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Published

1990-01-01

How to Cite

Hisamitsu, S., Shibuya, H., Hoshina, M., & Horiuchi, J. (1990). Prognostic Factors in Head and Neck Non-Hodgkin’s Lymphoma with Special Reference to Serum Lactic Dehydrogenase and Serum Copper. Acta Oncologica, 29(7), 879–883. https://doi.org/10.3109/02841869009096383