Immunoscintigraphy in Laryngeal and Pharyngeal Carcinomas Using Indium-111 Labelled Monoclonal Antibody

Authors

  • K. J. A. Kairemo Division of Nuclear Medicine, Central Laboratory, and Department of Otolaryngology, Helsinki University Central Hospital, Helsinki, Finland
  • E. V. M. Hopsu Division of Nuclear Medicine, Central Laboratory, and Department of Otolaryngology, Helsinki University Central Hospital, Helsinki, Finland

DOI:

https://doi.org/10.3109/02841869009090046

Keywords:

Larynx, pharynx, sqaumous cell carcinoma, adeno- carcinoma, monoclonal antibodies, immunoscintigraph

Abstract

Localization of primary tumors, metastases or recurrences in 13 consecutive patients with histological verification of squamous cell or adenocarcinoma was determined with radioimmunoscintigraphy using monoclonal radiolabelled anti-CEA-antibody. In 12 of the 13 cases, immunohistochemical stainings were positive for CEA. Correct radioimmunoscintigraphic localization was obtained in 15 of the 19 surgically verified tumor sites. There were two positive scintigraphic findings which could not be verified during one year follow-up. The CEA serum concentrations were with one exception normal in all patients, showing that the serum CEA level does not predict the possible benefit from anti-CEA radioimmunoscintigraphy.

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Published

1989-01-01

How to Cite

Kairemo, K. J. A. ., & Hopsu, E. V. M. . (1989). Immunoscintigraphy in Laryngeal and Pharyngeal Carcinomas Using Indium-111 Labelled Monoclonal Antibody. Acta Oncologica, 29(4), 533–538. https://doi.org/10.3109/02841869009090046

Issue

Vol. 29 No. 4 (1990): Acta Oncologica

Section

Articles