The Cancer Research Campaign Trials of Adjuvant Therapy for Early Breast Cancer

Authors

  • M. Baum The Cancer Research Campaign Clinical Trials Centre, and the Department of Surgery, King's College Hospital, London, England
  • S. R. Ebbs The Cancer Research Campaign Clinical Trials Centre, and the Department of Surgery, King's College Hospital, London, England
  • J. Houghton The Cancer Research Campaign Clinical Trials Centre, and the Department of Surgery, King's College Hospital, London, England
  • R. P. A'hern actaoncologica@mjspublishing.se
  • D. Riley The Cancer Research Campaign Clinical Trials Centre, and the Department of Surgery, King's College Hospital, London, England

DOI:

https://doi.org/10.3109/02841868909092330

Keywords:

Breast cancer, early, adjuvant trials, Cancer Research Campaign

Abstract

It is now assumed that for many women there has already been dissemination of turnour at the time of diagnosis of their early breast cancer. Systemic treatment is required if a cure is sought. the use of perioperative cyclophosphamide and long-term tam-oxifen, either as single agents or in combination, has been investigated in the Cancer Research Campaign Breast Adjuvant Trial. A total of 2230 women were recruited to the study. A benefit has been seen for both agents. the implications of these results for the current treatment of women with early breast cancer and for the design of future trials are discussed.

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Published

2009-01-01

How to Cite

Baum, M., Ebbs, S. R., Houghton, J., A’hern, R. P., & Riley, D. (2009). The Cancer Research Campaign Trials of Adjuvant Therapy for Early Breast Cancer. Acta Oncologica, 28(6), 907–91. https://doi.org/10.3109/02841868909092330

Issue

Vol. 28 No. 6 (1989): Acta Oncologica

Section

Articles