Blood Lymphocyte Population 4 to 6 Years after Adjuvant Cyclic Chemotherapy for Operable Breast Carcinoma

Authors

  • H. Blomgren RADIUMHEMMET, KAROLINSKA SJUKHUSET, S-10401, STOCKHOLM; THE CENTRAL MICROBIOLOGICAL LABORATORY OF STOCKHOLM COUNTY COUNCIL, S-10122, STOCKHOLM, SWEDEN
  • S. Rotstein RADIUMHEMMET, KAROLINSKA SJUKHUSET, S-10401, STOCKHOLM; THE CENTRAL MICROBIOLOGICAL LABORATORY OF STOCKHOLM COUNTY COUNCIL, S-10122, STOCKHOLM, SWEDEN
  • B. Petrini RADIUMHEMMET, KAROLINSKA SJUKHUSET, S-10401, STOCKHOLM; THE CENTRAL MICROBIOLOGICAL LABORATORY OF STOCKHOLM COUNTY COUNCIL, S-10122, STOCKHOLM, SWEDEN
  • J. Wasserman RADIUMHEMMET, KAROLINSKA SJUKHUSET, S-10401, STOCKHOLM; THE CENTRAL MICROBIOLOGICAL LABORATORY OF STOCKHOLM COUNTY COUNCIL, S-10122, STOCKHOLM, SWEDEN

DOI:

https://doi.org/10.3109/02841868509134374

Abstract

The influence of postoperative cyclic chemotherapy for breast carcinoma on the blood lymphocyte population was examined in 21 recurrence-free women 4 to 6 years after completion of therapy. Chemotherapy consisted of combinations of chlorambucil, methotrexate and 5-fluor-ouracil or cyclophosphamide, methotrexate and 5-fluor-ouracil. It was observed that the lymphocyte numbers and mitogenic responses to PHA and in an MLC, known to be depressed during and shortly after treatment, had recovered to the levels of healthy age-matched women. NK activity, which is increased during the period of chemotherapy, still remained elevated.

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Published

1985-01-01

How to Cite

Blomgren, H., Rotstein, S., Petrini, B., & Wasserman, J. (1985). Blood Lymphocyte Population 4 to 6 Years after Adjuvant Cyclic Chemotherapy for Operable Breast Carcinoma. Acta Oncologica, 24(2), 123–127. https://doi.org/10.3109/02841868509134374

Issue

Vol. 24 No. 2 (1985): Acta Radiologica: Oncology

Section

Articles