Adjuvant and Neoadjuvant Vincristine, Bleomycin, And Methotrexate for Inguinal Metastases from Squamous Cell Carcinoma of the Penis

Authors

  • G. Pizzocaro From the Section of Urologic Oncology, Istituto Nazionale Tumori, Milano, Italy
  • L. Piva From the Section of Urologic Oncology, Istituto Nazionale Tumori, Milano, Italy

DOI:

https://doi.org/10.3109/02841868809094366

Keywords:

Chemotherapy, penile cancer, lymph node metastases, vincristine, bleomycin, methotrexate

Abstract

Abstract

In a pilot study 12 patients with radically resected inguinal lymph node metastases from carcinoma of the penis and 5 patients with fixed inguinal nodes were treated with 12 weekly courses of vincristine, bleomycin and methotrexate (VBM). Only 1 of the 12 cases treated with adjuvant VBM relapsed after a median follow-up period of 42 months (range 18-102 months). Three partial responders to neoadjuvant VBM could have radical lymphadenectomy and they are alive disease-free 20, 27, 72 months after surgery. Two minimal responders could not have radical surgery and they died of the disease within one year.

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Published

1988-01-01

How to Cite

Pizzocaro, G., & Piva, L. (1988). Adjuvant and Neoadjuvant Vincristine, Bleomycin, And Methotrexate for Inguinal Metastases from Squamous Cell Carcinoma of the Penis. Acta Oncologica, 27(6), 823–824. https://doi.org/10.3109/02841868809094366

Issue

Vol. 27 No. 6 (1988): Acta Oncologica

Section

Articles