Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms

Authors

  • Gitte Dam a Department of Hepatology & Gastroenterology, ENETS Center of Excellence, Aarhus University Hospital, & Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
  • Henning Grønbæk a Department of Hepatology & Gastroenterology, ENETS Center of Excellence, Aarhus University Hospital, & Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
  • Anna Sundlöv b Division of Oncology, Department of Clinical Sciences Lund, Lund University, Sweden
  • Johan Botling c Department of Immunology Genetics and Pathology, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden
  • Anders Sundin d Department of Surgical Sciences, Radiology & Molecular Imaging, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden
  • Rene Horsleben Petersen e Department of Cardiothoracic Surgery, ENETS Center of Excellence, Copenhagen University Hospital, Rigshospitalet, Denmark; f Department of Clinical Medicine, University of Copenhagen, Denmark
  • Staffan Welin g Department of Medical Sciences, Endocrine Oncology Unit, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden
  • Espen-Thiis Evensen h Department for Organ Transplantation, Oslo University Hospital, ENETS Center of Excellence, Rikshospitalet, Oslo, Norway
  • Halfdan Sorbye i Department of Oncology, Haukeland University Hospital, and Department of Clinical Science, University of Bergen, Bergen, Norway
  • Elizaveta Tabaksblat j Department of Oncology, ENETS Center of Excellence, Aarhus University Hospital, Aarhus, Denmark
  • Anne Kirstine Arveschoug k Department of Nuclear Medicine & PET Center, Aarhus University Hospital, ENETS Center of Excellence, Aarhus, Denmark
  • Jann Mortensen Department. of Clinical Physiology and Nuclear Medicine, ENETS Center of Excellence & Cluster for Molecular Imaging, Copenhagen University Hospital–Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark
  • Andreas Kjaer l Department. of Clinical Physiology and Nuclear Medicine, ENETS Center of Excellence & Cluster for Molecular Imaging, Copenhagen University Hospital–Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark
  • Ulrich Knigge m Departments of Gastrointestinal Surgery and Clinical Endocrinology, ENETS Center of Excellence, Copenhagen University Hospital, Rigshospitalet, Denmark
  • Eva Tiensuu Janson g Department of Medical Sciences, Endocrine Oncology Unit, ENETS Center of Excellence, Uppsala University, Uppsala, Sweden
  • Seppo W. Langer n Department of Oncology, ENETS Center of Excellence, Copenhagen University Hospital, Rigshospitalet, and Dept. of Clinical Medicine, University of Copenhagen, Denmark

DOI:

https://doi.org/10.1080/0284186X.2023.2212411

Keywords:

Lung, neuroendocrine neoplasm, diagnosis, neuroendocrine carcinoma, bronchopulmonary neoplasm, treatment

Abstract

Lung neuroendocrine neoplasms (NEN) are a heterogeneous population of neoplasms with different pathology, clinical behavior, and prognosis compared to the more common lung cancers. The diagnostic work-up and treatment of patients with lung- NEN has undergone major recent advances and new methods are currently being introduced into the clinic. These Nordic guidelines summarize and update the Nordic Neuroendocrine Tumor Group’s current view on how to diagnose and treat lung NEN-patients and are meant to be useful in the daily practice for clinicians handling these patients. This review reflects our view of the current state of the art of diagnosis and treatment of patients with lung-NEN. Small cell lung carcinoma (SCLC) is not included in these guidelines.

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Published

2023-05-04

How to Cite

Dam, G., Grønbæk, H., Sundlöv, A., Botling, J., Sundin, A., Horsleben Petersen, R., … Langer, S. W. (2023). Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms. Acta Oncologica, 62(5), 431–437. https://doi.org/10.1080/0284186X.2023.2212411