Effects of home-based specialized palliative care and dyadic psychological intervention on caregiver burden: results from a randomized controlled trial

Authors

  • Annika von Heymann a Psychological Aspects of Cancer, Danish Cancer Society Research Center, Copenhagen, Denmark; b Cancer Survivorship and Treatment Late Effects, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  • Emma Finsted a Psychological Aspects of Cancer, Danish Cancer Society Research Center, Copenhagen, Denmark
  • Mai-Britt Guldin c Research Unit for General Practice, Public Health, Aarhus University, Aarhus, Denmark
  • Elisabeth Anne Wreford Andersen d Unit of Statistics and Pharmacoepidemiology, Danish Cancer Society Research Center, Copenhagen, Denmark
  • Jesper Dammeyer e Department of Psychology, University of Copenhagen, Copenhagen, Denmark
  • Per Sjøgren f Palliative Research Group, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  • Hans von der Maase b Cancer Survivorship and Treatment Late Effects, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  • Kirstine S. Benthien g Palliative Care Unit, Copenhagen University Hospital, Hvidovre, Denmark; h Center for Clinical Research and Prevention, Frederiksberg Hospital, Copenhagen, Denmark
  • Jakob Kjellberg i VIVE, The Danish Center for Social Science Research, Copenhagen, Denmark
  • Christoffer Johansen a Psychological Aspects of Cancer, Danish Cancer Society Research Center, Copenhagen, Denmark; b Cancer Survivorship and Treatment Late Effects, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  • Pernille Bidstrup a Psychological Aspects of Cancer, Danish Cancer Society Research Center, Copenhagen, Denmark; e Department of Psychology, University of Copenhagen, Copenhagen, Denmark

DOI:

https://doi.org/10.1080/0284186X.2023.2194491

Keywords:

Cancer, oncology, family caregiver, palliative care, psychological intervention

Abstract

Background The Domus study, a randomized controlled trial (RCT), evaluated the effect of home-based specialized palliative care (SPC) reinforced with a psychological intervention for the patient-caregiver dyad on increasing advanced cancer patients’ time spent at home, as opposed to hospitalized, and the number of home deaths. As palliative care extends to include support for patients’ families and may thus assist caregivers and decrease demands on them, in this study we evaluated a secondary outcome, caregiver burden.

Material and Methods Patients with incurable cancer and their caregivers were randomized (1:1) to care as usual or home-based SPC. Caregiver burden was assessed using the Zarit Burden Interview (ZBI) at baseline and 2, 4, 8 weeks and 6 months after randomization. Intervention effects were assessed in mixed effects models.

Results A total of 258 caregivers were enrolled. Eleven per cent of informal caregivers experienced severe caregiver burden at baseline. Caregiver burden increased significantly over time in both groups (p = 0.0003), but no significant effect of the intervention was seen on overall caregiver burden (p = 0.5046) or burden subscales measuring role and personal strain.

Conclusion In line with the majority of previous RCTs, the Domus intervention was not able to significantly reduce caregiver burden. Future interventions should consider targeting only caregivers reporting the greatest caregiver burden.

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Published

2023-07-03

How to Cite

von Heymann, A., Finsted, E., Guldin, M.-B., Wreford Andersen, E. A., Dammeyer, J., Sjøgren, P., … Bidstrup, P. (2023). Effects of home-based specialized palliative care and dyadic psychological intervention on caregiver burden: results from a randomized controlled trial. Acta Oncologica, 62(7), 803–807. https://doi.org/10.1080/0284186X.2023.2194491

Issue

Vol. 62 No. 7 (2023): Acta Oncologica

Section

Articles