Treatment patterns in patients with locally advanced and metastatic bladder cancer in Denmark 2015-2023 – an updated analysis

Authors

  • Mette Nørgaard Department of Clinical Epidemiology, Arhus University Hospital and Department of Clinical Medicine, Aarhus University, Aarhus, Denmark https://orcid.org/0000-0001-6110-5891
  • Aurélie Mailhac Department of Clinical Epidemiology, Arhus University Hospital and Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
  • Karin Fagerlund Astellas Pharma A/S - Nordic Operation, Copenhagen, Denmark
  • Torsten Strunz-McKendry Astellas Pharma Europe Ltd, Addlestone, UK https://orcid.org/0000-0001-6032-8794
  • Mads Agerbæk Department of Oncology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
  • Jørgen Bjerggaard Jensen Department of Urology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Aarhus, Denmark https://orcid.org/0000-0002-4347-739X

DOI:

https://doi.org/10.2340/1651-226X.2025.43484

Keywords:

Bladder cancer, treatment patterns, nationwide cohort study

Downloads

Download data is not yet available.

References

Nørgaard M, Mailhac A, Fagerlund K, Strunz-McKendry T, Agerbæk M, Jensen JB. Treatment patterns, survival, and healthcare utilisation and costs in patients with locally advanced and metastatic bladder cancer in Denmark 2015–2020. Acta Oncol (Stockholm, Sweden). 2023;62(12):1784–90.

https://doi.org/10.1080/0284186X.2023.2263154 DOI: https://doi.org/10.1080/0284186X.2023.2263154

Rosenkrantz O, Wheler J, Westphal Thrane MC, Pedersen L, Sørensen HT. The Danish National Hospital Medication Register: a resource for pharmacoepidemiology. Clin Epidemiol. 2024;16:783–92.

https://doi.org/10.2147/CLEP.S487838 DOI: https://doi.org/10.2147/CLEP.S487838

Schmidt M, Schmidt SAJ, Adelborg K, Sundboll J, Laugesen K, Ehrenstein V, et al. The Danish health care system and epidemiological research: from health care contacts to database records. Clin Epidemiol. 2019;11:563–91.

https://doi.org/10.2147/CLEP.S179083

Schmidt M, Pedersen L, Sorensen HT. The Danish Civil Registration System as a tool in epidemiology. Eur J Epidemiol. 2014;29(8):541–9. DOI: https://doi.org/10.1007/s10654-014-9930-3

https://doi.org/10.2147/CLEP.S179083 DOI: https://doi.org/10.2147/CLEP.S179083

Schmidt M, Schmidt SA, Sandegaard JL, Ehrenstein V, Pedersen L, Sorensen HT. The Danish National Patient Registry: a review of content, data quality, and research potential. Clin Epidemiol. 2015;7:449–90.

https://doi.org/10.2147/CLEP.S91125 DOI: https://doi.org/10.2147/CLEP.S91125

Bjerregaard B, Larsen OB. The Danish Pathology Register. Scand J Public Health. 2011;39(7 Suppl):72–4.

https://doi.org/10.1177/1403494810393563 DOI: https://doi.org/10.1177/1403494810393563

Erichsen R, Lash TL, Hamilton-Dutoit SJ, Bjerregaard B, Vyberg M, Pedersen L. Existing data sources for clinical epidemiology: the Danish National Pathology Registry and Data Bank. Clin Epidemiol. 2010;2:51–6.

https://doi.org/10.2147/CLEP.S9908 DOI: https://doi.org/10.2147/CLEP.S9908

Sørup S, Darvalics B, Knudsen JS, Rasmussen AS, Hjorth CF, Vestergaard SV, et al. Identifying valid algorithms for number of lines of anti-neoplastic therapy in the Danish National Patient Registry among patients with advanced ovarian, gastric, renal cell, urothelial, and non-small cell lung cancer attending a Danish University Hospital. Clin Epidemiol. 2022;14:159–71.

https://doi.org/10.2147/CLEP.S342238 DOI: https://doi.org/10.2147/CLEP.S342238

Geynisman DM, Broughton E, Hao Y, Zhang Y, Le T, Huo S. Real-world treatment patterns and clinical outcomes among patients with advanced urothelial carcinoma in the United States. Urol Oncol. 2022;40(5):195.e1–e11.

https://doi.org/10.1016/j.urolonc.2021.11.014 DOI: https://doi.org/10.1016/j.urolonc.2021.11.014

Richters A, Mehra N, Meijer RP, Boormans JL, van der Heijden AG, Smilde TJ, et al. Utilization of systemic treatment for metastatic bladder cancer in everyday practice: results of a nation-wide population-based cohort study. Cancer Treat Res Commun. 2020;25:100266.

https://doi.org/10.1016/j.ctarc.2020.100266 DOI: https://doi.org/10.1016/j.ctarc.2020.100266

Swami U, Grivas P, Pal SK, Agarwal N. Utilization of systemic therapy for treatment of advanced urothelial carcinoma: lessons from real world experience. Cancer Treat Res Commun. 2021;27:100325.

https://doi.org/10.1016/j.ctarc.2021.100325 DOI: https://doi.org/10.1016/j.ctarc.2021.100325

Goebell PJ, Radkowski R, Müller L, Ghasemi U, Grünwald V, Deger S, et al. A0753 – first-line maintenance therapy in patients with locally advanced or metastatic urothelial carcinoma in routine care in Germany: preliminary results of the prospective CARAT registry. Eur Urol. 2024;85:S1731.

https://doi.org/10.1016/S0302-2838(24)01324-1 DOI: https://doi.org/10.1016/S0302-2838(24)01324-1

Puente J, Pinto A, Mendez-Vidal MJ, García Del Muro X, Maroto P, Vazquez S, et al. Real-world treatment patterns, survival outcomes, and health care resource utilization for locally advanced or metastatic urothelial carcinoma in Spain. Clin Transl Oncol. 2025;27:2232-40.

https://doi.org/10.1007/s12094-024-03734-8 DOI: https://doi.org/10.1007/s12094-024-03734-8

Joly F, Culine S, Roupret M, Tricotel A, Casarotto E, Brice S, et al. Epidemiology, resource use, and treatment patterns of locally advanced or metastatic urothelial carcinoma in France. Future Oncol. 2025;21(6):1–15.

https://doi.org/10.1080/14796694.2025.2459058 DOI: https://doi.org/10.1080/14796694.2025.2459058

Hansen E, Larsson H, Norgaard M, Thind P, Jensen JB. The Danish Bladder Cancer Database. Clinical epidemiology. 2016;8:439-43. DOI: https://doi.org/10.2147/CLEP.S99491

Published

2025-05-07

How to Cite

Nørgaard, M., Mailhac, A., Fagerlund, K., Strunz-McKendry, T., Agerbæk, M., & Jensen, J. B. (2025). Treatment patterns in patients with locally advanced and metastatic bladder cancer in Denmark 2015-2023 – an updated analysis. Acta Oncologica, 64, 630–632. https://doi.org/10.2340/1651-226X.2025.43484