The levels of circulating tumor DNA and inflammatory proteins depict the clinical response in a patient with metastatic undifferentiated pleomorphic sarcoma, a case report

Authors

  • Christoffer Vannas Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Oncology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden https://orcid.org/0000-0002-1029-0393
  • Mandy Escobar Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden https://orcid.org/0000-0002-9095-1429
  • Margaréta Tanyasiová Department of Oncology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden
  • Mathilda Kindeberg Sederblad Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Oncology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden
  • Julia Nyström Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
  • Tobias Österlund Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden https://orcid.org/0000-0002-7870-8645
  • David Wennergren Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden https://orcid.org/0000-0001-9882-6414
  • Daniel Andersson Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden https://orcid.org/0000-0002-4564-6652
  • Martin Dalin Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden; Children's Cancer Centre, Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden; Sahlgrenska Center for Cancer Research, Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden https://orcid.org/0000-0002-7516-0004
  • Åsa Torinsson Naluai Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; Core Facilities, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden https://orcid.org/0000-0002-0504-6492
  • Henrik Fagman Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Clinical Pathology, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden https://orcid.org/0000-0001-5853-6295
  • Anders Ståhlberg Sahlgrenska Center for Cancer Research, Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden; Science for Life Laboratory, Institute of Biomedicine, University of Gothenburg, Sweden https://orcid.org/0000-0003-4243-0191

DOI:

https://doi.org/10.2340/1651-226X.2025.44337

Keywords:

circulating tumor DNA, liquid biopsy, Sarcoma, proteomics, Malignant Fibrous Histiocytoma, multiomics, case report

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References

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Published

2025-09-11

How to Cite

Vannas, C., Escobar, M., Tanyasiová, M., Kindeberg Sederblad, M., Nyström, J., Österlund, T., … Ståhlberg, A. (2025). The levels of circulating tumor DNA and inflammatory proteins depict the clinical response in a patient with metastatic undifferentiated pleomorphic sarcoma, a case report. Acta Oncologica, 64, 1212–1216. https://doi.org/10.2340/1651-226X.2025.44337