Gastrointestinal risk assessment in patients requiring non-steroidal anti-inflammatory drugs for osteoarthritis: The GIRANO study.

Authors

  • Guy Vanderstraeten
  • Thierry M. Lejeune
  • Hubert Piessevaux
  • Dirk De Bacquer
  • Chris Walker
  • Birgit De Beleyr

DOI:

https://doi.org/10.2340/16501977-2119

Keywords:

gastrointestinal risk, non-steroidal anti-inflammatory drug, osteoarthritis, primary care.

Abstract

OBJECTIVE: To evaluate gastrointestinal risk profiles in patients with osteoarthritis who are currently being treated, or who are candidates for treatment, with a non-steroidal anti-inflammatory drug. METHODS: Patients with osteoarthritis treated by primary care physicians or physical and rehabilitation medicine (PRM) specialists in Belgium and Luxembourg were scored for gastrointestinal risk profile, low, moderate or high, based on the presence of gastrointestinal risk factors. These included advanced age, gastrointestinal history, comorbidities, medication use, smoking, and alcohol consumption. Use of gastro-protective agents (proton pump inhibitors) was also assessed. RESULTS: A total of 190 primary care physicians and PRM specialists provided data on 885 patients. A large majority of patients were rated high-risk gastrointestinal (77.8%), with fewer moderate (19.4%) or low (2.8%) risk. The proportion of high-risk patients treated by PRM specialists was significantly lower than that treated by primary care physicians (64.7% vs 79.9%

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Published

2016-06-27

How to Cite

Vanderstraeten, G., Lejeune, T. M., Piessevaux, H., De Bacquer, D., Walker, C., & De Beleyr, B. (2016). Gastrointestinal risk assessment in patients requiring non-steroidal anti-inflammatory drugs for osteoarthritis: The GIRANO study. Journal of Rehabilitation Medicine, 48(8), 705–710. https://doi.org/10.2340/16501977-2119

Issue

Section

Original Report