Factors associated with fatigue among people who have returned to work after stroke: an exploratory study

Authors

  • Anna Norlander Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden; Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics, Skåne University Hospital, Lund, Sweden
  • Ingrid Lindgren Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden; Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics, Skåne University Hospital, Lund, Sweden
  • Christina Brogårdh Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden; Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics, Skåne University Hospital, Lund, Sweden

DOI:

https://doi.org/10.2340/jrm.v56.18668

Keywords:

Cerebral Stroke, Cross-Sectional Studies, Fatigue, Follow-Up Studies, Regression analysis, Return to Work, Self Report, Stroke Rehabilitation

Abstract

Objective: To explore the associations between fatigue impact and (a) personal and stroke-related characteristics, (b) functional impairments and (c) work-related factors among individuals who have returned to work after stroke.

Design: A cross-sectional exploratory study.

Subjects: 87 working stroke survivors.

Methods: This study comprises data from a postal survey targeting work ability and perceived stroke-related consequences 1 year after stroke. Fatigue was evaluated using the Fatigue Severity Scale (FSS). Factors associated with having fatigue (FSS total score ≥ 4) were identified using univariable and multivariable logistic regression analyses. Three domain-specific multivariable models and 1 final combined model were created.

Results: Fatigue was reported by 43% of the participants. Several factors representing all the investigated domains were associated with fatigue. In the final combined regression model, self-perceived low cognitive functioning, low decision control at work and high quantitative job demands had the strongest independent effects on the odds of having fatigue.

Conclusion: Among people who were working 1 year after stroke, fatigue was associated with both personal and stroke-related characteristics as well as functional impairments and work-related factors. This highlights the complex nature of post-stroke fatigue. Fatigue management interventions should have a comprehensive approach and also consider the work environment.

Downloads

Download data is not yet available.

References

Feigin VL, Norrving B, Mensah GA. Global burden of stroke. Circ Res 2017; 120: 439–448. DOI: https://doi.org/10.1161/CIRCRESAHA.116.308413

https://10.1161/CIRCRESAHA.116.308413

Adamson J, Beswick A, Ebrahim S. Is stroke the most common cause of disability? J Stroke Cerebrovasc Dis 2004; 13: 171–177. DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2004.06.003

https://10.1016/j.jstrokecerebrovasdis.2004.06.003

Socialstyrelsen. Statistik om Stroke 2022. Stockholm: Socialstyrelsen; 2023. ISSN 1400-3511.

Alguren B, Lundgren-Nilsson A, Sunnerhagen KS. Functioning of stroke survivors: a validation of the ICF core set for stroke in Swe-den. Disabil Rehabil 2010; 32: 551–559. DOI: https://doi.org/10.3109/09638280903186335

https://10.3109/09638280903186335

Paanalahti M, Berzina G, Lundgren-Nilsson A, Arndt T, Sunnerhagen KS. Examination of the relevance of the ICF cores set for stroke by comparing with the Stroke Impact Scale. Disabil Rehabil 2019; 41: 508–513. DOI: https://doi.org/10.1080/09638288.2017.1396368

https://10.1080/09638288.2017.1396368

Crosby GA, Munshi S, Karat AS, Worthington E, Lincoln NB. Fatigue after stroke: frequency and effect on daily life. Disabil Rehabil 2012; 34: 633–637. DOI: https://doi.org/10.3109/09638288.2011.613517

https://10.3109/09638288.2011.613517

Carlsson GE, Möller A, Blomstrand C. Consequences of mild stroke in persons < 75 years: a 1-year follow-up. Cerebrovasc Dis 2003; 16: 383–388. DOI: https://doi.org/10.1159/000072561

https://10.1159/000072561

Kirchberger I, Wallner F, Linseisen J, Zickler P, Ertl M, Naumann M, et al. Factors associated with early and late post-stroke fati-gue in patients with mild impairment. results from the Stroke Cohort Study Augsburg. Front Neurol 2022; 13: 852486. DOI: https://doi.org/10.3389/fneur.2022.852486

https://10.3389/fneur.2022.852486

Terrill AL, Schwartz JK, Belagaje SR. Best practices for the interdisciplinary rehabilitation team: a review of mental health issues in mild stroke survivors. Stroke Res Treat 2018; 2018: 6187328. DOI: https://doi.org/10.1155/2018/6187328

https://10.1155/2018/6187328

Cumming TB, Packer M, Kramer SF, English C. The prevalence of fatigue after stroke: a systematic review and meta-analysis. Int J Stroke 2016; 11: 968–977. DOI: https://doi.org/10.1177/1747493016669861

https://10.1177/1747493016669861

Aarnes R, Stubberud J, Lerdal A. A literature review of factors associated with fatigue after stroke and a proposal for a framework for clinical utility. Neuropsychol Rehabil 2020; 30: 1449–1476. DOI: https://doi.org/10.1080/09602011.2019.1589530

https://10.1080/09602011.2019.1589530

Radman N, Staub F, Aboulafia-Brakha T, Berney A, Bogousslavsky J, Annoni M. Poststroke fatigue following minor infarcts: a prospective study. Neurology 2012; 79: 1422–1427. DOI: https://doi.org/10.1212/WNL.0b013e31826d5f3a

https://10.1212/WNL.0b013e31826d5f3a

White JH, Gray KR, Magin P, Attia J, Sturm J, Carter G, et al. Exploring the experience of post-stroke fatigue in community dwelling stroke survivors: a prospective qualitative study. Disabil Rehabil 2012; 34: 1376–1384. DOI: https://doi.org/10.3109/09638288.2011.645111

https://10.3109/09638288.2011.645111

Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Health-related quality of life among young adults with ischemic stroke on long-term follow-up. Stroke 2006; 37: 1232–1236. DOI: https://doi.org/10.1161/01.STR.0000217652.42273.02

https://10.1161/01.STR.0000217652.42273.02

Tang WK, Lu JY, Chen YK, Mok VC, Ungvari GS, Wong KS. Is fatigue associated with short-term health-related quality of life in stroke? Arch Phys Med Rehabil 2010; 91: 1511–1515. DOI: https://doi.org/10.1016/j.apmr.2010.06.026

https://10.1016/j.apmr.2010.06.026

Della Vecchia C, Préau M, Carpentier C, Viprey M, Haesebaert J, Termoz A, et al. Illness beliefs and emotional responses in mildly disabled stroke survivors: a qualitative study. PLoS One 2019; 14: e0223681. DOI: https://doi.org/10.1371/journal.pone.0223681

https://10.1371/journal.pone.0223681

Andersen G, Christensen D, Kirkevold M, Johnsen SP. Post-stroke fatigue and return to work: a 2-year follow-up. Acta Neurol Scand 2012; 125: 248–253. DOI: https://doi.org/10.1111/j.1600-0404.2011.01557.x

https://10.1111/j.1600-0404.2011.01557.x

Balasooriya-Smeekens C, Bateman A, Mant J, De Simoni A. Barriers and facilitators to staying in work after stroke: insight from an online forum. BMJ Open 2016; 6: e009974. DOI: https://doi.org/10.1136/bmjopen-2015-009974

https://10.1136/bmjopen-2015-009974

Palstam A, Törnbom M, Stibrandt Sunnerhagen K. Experiences of returning to work and maintaining work 7 to 8 years after a stroke: a qualitative interview study in Sweden. BMJ Open 2018; 8: e021182. DOI: https://doi.org/10.1136/bmjopen-2017-021182

https://10.1136/bmjopen-2017-021182

Norlander A, Lindgren I, Pessah-Rasmussen H, Gard G, Brogårdh C. Fatigue in men and women who have returned to work after stroke: assessed with the Fatigue Severity Scale and Mental Fatigue Scale. J Rehabil Med 2021; 53: jrm00227. DOI: https://doi.org/10.2340/16501977-2863

https://10.2340/16501977-2863

Wu S, Mead G, Macleod M, Chalder T. Model of understanding fatigue after stroke. Stroke 2015; 46: 893–898. DOI: https://doi.org/10.1161/STROKEAHA.114.006647

https://10.1161/STROKEAHA.114.006647

Paciaroni M, Acciarresi M. Poststroke fatigue. Stroke 2019; 50: 1927–1933. DOI: https://doi.org/10.1161/STROKEAHA.119.023552

https://10.1161/STROKEAHA.119.023552

Chen K, Marsh EB. Chronic post-stroke fatigue: it may no longer be about the stroke itself. Clin Neurol Neurosurg 2018; 174: 192–197. DOI: https://doi.org/10.1016/j.clineuro.2018.09.027

https://10.1016/j.clineuro.2018.09.027

Kirkevold M, Christensen D, Andersen G, Johansen SP, Harder I. Fatigue after stroke: manifestations and strategies. Disabil Rehabil 2012; 34: 665–670. DOI: https://doi.org/10.3109/09638288.2011.615373

https://10.3109/09638288.2011.615373

Eilertsen G, Ormstad H, Kirkevold M. Experiences of poststroke fatigue: qualitative meta-synthesis. J Adv Nurs 2013; 69: 514–525. DOI: https://doi.org/10.1111/jan.12002

https://10.1111/jan.12002

Lindgren I, Pessah-Rasmussen H, Gard G, Brogårdh C. Perceived work situation and work ability among persons who are working one year after stroke. J Rehabil Med 2022; 54: jrm00254. DOI: https://doi.org/10.2340/jrm.v53.918

https://10.2340/jrm.v53.918

Lindgren I, Brogårdh C, Pessah-Rasmussen H, Jonasson SB, Gard G. Work conditions, support, and changing personal priorities are perceived important for return to work and for stay at work after stroke: a qualitative study. Disabil Rehabil 2022; 44: 2500–2506. DOI: https://doi.org/10.1080/09638288.2020.1836522

https://10.1080/09638288.2020.1836522

Garland A, Jeon SH, Stepner M, Rotermann M, Fransoo R, Wunsch H, et al. Effects of cardiovascular and cerebrovascular health events on work and earnings: a population-based retrospective cohort study. CMAJ 2019; 191: E3–E10. DOI: https://doi.org/10.1503/cmaj.181238

https://10.1503/cmaj.181238

Gard G, Pessah-Rasmussen H, Brogårdh C, Nilsson Å, Lindgren I. Need for structured healthcare organization and support for return to work after stroke in Sweden: experiences of stroke survivors. J Rehabil Med 2019; 51: 741–748. DOI: https://doi.org/10.2340/16501977-2591

https://10.2340/16501977-2591

Mattsson M, Möller B, Lundberg IE, Gard G, Boström C. Reliability and validity of the Fatigue Severity Scale in Swedish for patients with systemic lupus erythematosus. Scand J Rheumatol 2008; 37: 269–277. DOI: https://doi.org/10.1080/03009740801914868

https://10.1080/03009740801914868

Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale: application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 1989; 46: 1121–1123. DOI: https://doi.org/10.1001/archneur.1989.00520460115022

https://10.1001/archneur.1989.00520460115022

Alghamdi I, Ariti C, Williams A, Wood E, Hewitt J. Prevalence of fatigue after stroke: a systematic review and meta-analysis. Eur Stroke J 2021; 6: 319–332. DOI: https://doi.org/10.1177/23969873211047681

https://10.1177/23969873211047681

Ozyemisci-Taskiran O, Batur EB, Yuksel S, Cengiz M, Karatas GK. Validity and reliability of fatigue severity scale in stroke. Top Stroke Rehabil 2019; 26: 122–127. DOI: https://doi.org/10.1080/10749357.2018.1550957

https://10.1080/10749357.2018.1550957

Nadarajah M, Mazlan M, Abdul-Latif L, Goh HT. Test–retest reliability, internal consistency and concurrent validity of Fatigue Severi-ty Scale in measuring post-stroke fatigue. Eur J Phys Rehabil Med 2017; 53: 703–709. DOI: https://doi.org/10.23736/S1973-9087.16.04388-4

https://10.23736/S1973-9087.16.04388-4

Mulder M, Nijland R. Stroke Impact Scale. J Physiother 2016; 62: 117. DOI: https://doi.org/10.1016/j.jphys.2016.02.002

https://10.1016/j.jphys.2016.02.002

Schwarzer R, Jerusalem M. Generalized self-efficacy scale. In: Weiman J, Wright S, Johnston M, editors. Measures in health psychology: a user’s portfolio. Causal and control beliefs. Windsor: NferNelson; 1995, p 35–37. DOI: https://doi.org/10.1037/t00393-000

Scholz U, Doña BG, Sud S, Schwarzer R. Is general self-efficacy a universal construct? Psychometric findings from 25 countries. Eur J Psychol Assess 2002; 18: 242–251. DOI: https://doi.org/10.1027//1015-5759.18.3.242

https://10.1027//1015-5759.18.3.242

Carlstedt E, Månsson Lexell E, Pessah-Rasmussen H, Iwarsson S. Psychometric properties of the Swedish version of the General Self-Efficacy Scale in stroke survivors. Int J Rehabil Res 2015; 38: 333–337. DOI: https://doi.org/10.1097/MRR.0000000000000131

https://10.1097/MRR.0000000000000131

Wännström I, Peterson U, Asberg M, Nygren A, Gustavsson JP. Psychometric properties of scales in the General Nordic Quest-ionnaire for Psychological and Social Factors at Work (QPS): confirmatory factor analysis and prediction of certified long-term sickness absence. Scand J Psychol 2009; 50: 231–244. DOI: https://doi.org/10.1111/j.1467-9450.2008.00697.x

https://10.1111/j.1467-9450.2008.00697.x

Dalgard OS, Sorensen T, Sandanger I, Nygård JF, Svensson E, Reas DL. Job demands, job control, and mental health in an 11-year follow-up study: normal and reversed relationships. Work Stress 2009; 23: 284–296. DOI: https://doi.org/10.1080/02678370903250953

https://10.1080/02678370903250953

La Torre G, Lia L, Francavilla F, Chiappetta M, De Sio S. Factors that facilitate and hinder the return to work after stroke: an over-view of systematic reviews. Med Lav 2022; 113: e2022029.

https://10.23749/mdl.v113i3.13238

Pedersen A, Almkvist E, Holmegaard L, Lagging C, Redfors P, Blomstrand C, et al. Fatigue 7 years post-stroke: predictors and corre-lated features. Acta Neurol Scand 2022; 146: 295–303. DOI: https://doi.org/10.1111/ane.13665

https://10.1111/ane.13665

Parks NE, Eskes GA, Gubitz GJ, Reidy Y, Christian C, Phillips SJ. Fatigue impact scale demonstrates greater fatigue in younger stroke survivors. Can J Neurol Sci 2012; 39: 619–625. DOI: https://doi.org/10.1017/S0317167100015353

https://10.1017/s0317167100015353

Ray C, Jefferies S, Weir WR. Coping and other predictors of outcome in chronic fatigue syndrome: a 1-year follow-up. J Psychosom Res 1997; 43: 405–415. DOI: https://doi.org/10.1016/S0022-3999(97)00111-6

https://10.1016/s0022-3999(97)00111-6

Johansson B, Rönnbäck L. Evaluation of the Mental Fatigue Scale and its relation to cognitive and emotional functioning after trauma-tic brain injury or stroke. Int J Phys Med Rehabil 2014; 2: 182.

https://10.4172/2329-9096.1000182

Knudsen AK, Hotopf M, Skogen JC, Overland S, Mykletun A. The health status of nonparticipants in a population-based health study: the Hordaland Health Study. Am J Epidemiol 2010; 172: 1306–1314. DOI: https://doi.org/10.1093/aje/kwq257

https://10.1093/aje/kwq257

Published

2024-03-14

How to Cite

Norlander, A., Lindgren, I., & Brogårdh, C. (2024). Factors associated with fatigue among people who have returned to work after stroke: an exploratory study. Journal of Rehabilitation Medicine, 56, jrm18668. https://doi.org/10.2340/jrm.v56.18668

Issue

Section

Original Report

Categories