Health-related quality of life and participation after inpatient rehabilitation of sepsis survivors with severe sequelae: a cohort study

Authors

  • Ulf Bodechtel Klinik Bavaria in Kreischa, Kreischa, Germany
  • Thea Koch Klinik für Anästhesiologie und Intensivtherapie, Medizinische Fakultät ‚Carl Gustav Carus‘, Technische Universität Dresden, Dresden, Germany
  • Lars Heubner Klinik für Anästhesiologie und Intensivtherapie, Medizinische Fakultät ‚Carl Gustav Carus‘, Technische Universität Dresden, Dresden, Germany
  • Peter Spieth Klinik für Anästhesiologie und Intensivtherapie, Medizinische Fakultät ‚Carl Gustav Carus‘, Technische Universität Dresden, Dresden, Germany
  • Ines Rößler Klinik Bavaria in Kreischa, Kreischa, Germany
  • Jan Mehrholz Wissenschaftliches Institut, Private Europäische Medizinische Akademie der Klinik Bavaria in Kreischa, Kreischa, Germany; Department of Public Health, Medizinische Fakultät ‚Carl Gustav Carus‘, Technische Universität Dresden, Germany

DOI:

https://doi.org/10.2340/jrm.v56.18670

Keywords:

Quality of Life, Rehabilitation, Sepsis, Social Participation

Abstract

Objective: To describe health-related quality of life and participation after rehabilitation of severely affected sepsis survivors.

Design: Cohort study.

Subjects/Patients: Patients with severe sequelae after sepsis treated in a multidisciplinary rehabilitation pathway were included.

Methods: Patient characteristics at the time of diagnosis, and the outcome 3 months after discharge from rehabilitation are described. At that time, health-related quality of life, social participation, and the rate of living at home were measured.

Results: Of the 498 patients enrolled, 100 severely impaired patients were transferred for a multidisciplinary rehabilitation approach. Fifty-five of them were followed up at 3 months. Descriptive and inference statistics showed that 69% were living at home with or without care. Health-related quality of life and participation scores were 0.64 ± 0.32 for the EQ-5D utility index and 54.98 ± 24.97 for the Reintegration of Normal Living Index. A multivariate regression model explaining health-related quality of life at 3 months included age, lower limb strength, and walking ability during rehabilitation (r2 = 0.5511). Participation at 3 months was explained by age, body mass index, lower limb strength, and duration of tracheal intubation (r2 = 0.6229).

Conclusion: Patients who have experienced serious sepsis with severe sequelae can achieve a moderate level of quality of life and participation within a multidisciplinary pathway.

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Published

2024-07-02

How to Cite

Bodechtel, U. ., Koch, T. ., Heubner, L. ., Spieth, P. ., Rößler, I. ., & Mehrholz, J. (2024). Health-related quality of life and participation after inpatient rehabilitation of sepsis survivors with severe sequelae: a cohort study. Journal of Rehabilitation Medicine, 56, jrm18670. https://doi.org/10.2340/jrm.v56.18670

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