The effectiveness and costs of intensive stroke rehabilitation and improvements in patient pathway in Finland: a retrospective benchmarking controlled trial

Authors

  • Niko Korpi Doctoral Programme in Clinical Research University of Helsinki, and Head Physician, Orimattila Health Center, Wellbeing services county of Päijät-Häme, Lahti, Finland
  • Marja Mikkelsson University of Helsinki, and Chief physician, Department of Rehabilitation, Wellbeing services county of Päijät-Häme Lahti, Finland
  • Unto Häkkinen Finnish Institute for Health and Welfare, Helsinki, Finland
  • Antti Malmivaara National Institute for Health and Welfare, Helsinki, Finland; Orton Orthopaedic Hospital, Helsinki, Finland

DOI:

https://doi.org/10.2340/jrm.v56.34944

Keywords:

stroke, rehabilitation, rehabilitation centre, interprofessional, rehabilitation pathway, PERFECT, effectiveness, cost-effectiveness

Abstract

Objective: To assess the effectiveness and costs of intensive stroke rehabilitation and improvements in patient pathway in the city of Lahti and in Päijät-Häme region compared with other parts in Finland.

Design: Retrospective benchmarking controlled trial.

Patients: Three cohorts of Finnish community-dwelling patients (n = 94,749, n = 4,184, and n = 105,458) with ischaemic stroke between 2001 and 2019.

Methods: This study is based on the PERFECT 2001–2019 database of ischaemic stroke patients. PERFECT indicators describe how the stroke patients recover. The difference-in-difference method was used in the main analysis.

Results: Improved stroke rehabilitation in Lahti increased the share of patients discharged home (p = 0.005) and decreased the length of first institutional episode (–4 days, p = 0.006), the share of patients institutionalized (–5.1%, p = 0.001), and the costs of first institutional episode (€–2,085, p < 0.001) compared with the rest of Finland. Discharges to home increased 6.6 percentage points (p = 0.021) in Lahti compared with rest of Päijät-Häme. After 2013, the costs of first institutional episode per patient in Päijät-Häme decreased significantly compared with the rest of Finland (p < 0.001).

Conclusion: Investments in intensive stroke rehabilitation and patient pathway seem to provide both faster and better return to home for patients and reduced costs for the healthcare system.

Downloads

Download data is not yet available.

Author Biographies

Marja Mikkelsson, University of Helsinki, and Chief physician, Department of Rehabilitation, Wellbeing services county of Päijät-Häme Lahti, Finland

PhD, professor of Rehabilitation, Faculty of Medicine, University of Helsinki, and Chief physician, Department of Rehabilitation, Wellbeing services county of Päijät-Häme

Unto Häkkinen, Finnish Institute for Health and Welfare, Helsinki, Finland

PhD, Senior Specialist, Research Professor (emeritus), Centre for Health and Social Economics, Finnish Institute for Health and Welfare, Helsinki, Finland

Antti Malmivaara, National Institute for Health and Welfare, Helsinki, Finland; Orton Orthopaedic Hospital, Helsinki, Finland

PhD, professor, Assessment of the Health and Social Service System, National Institute for Health and Welfare, Helsinki, Finland; Orton Orthopaedic Hospital, Helsinki, Finland

References

Pereira S, Graham JR, Shahabaz A, Salter K, Foley N, Meyer M, et al. Rehabilitation of individuals with severe stroke: synthesis of best evidence and challenges in implementation. Top Stroke Rehabil 2015; 19: 122–131.

https://doi.org/10.1310/TSR1902-122 DOI: https://doi.org/10.1310/tsr1902-122

Rønning OM, Guldvog B. Outcome of subacute stroke rehabilitation. Stroke 1998; 29: 779–784.

https://doi.org/10.1161/01.STR.29.4.779 DOI: https://doi.org/10.1161/01.STR.29.4.779

Langhorne P. Organised inpatient (stroke unit) care for stroke Cochrane Database Syst Rev 2013; 2013: CD000197.

https://doi.org/10.1002/14651858.CD000197.pub3 DOI: https://doi.org/10.1002/14651858.CD000197.pub3

Hacke W, Donnan G, Fieschi C, Kaste M. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004; 363: 768–774.

https://doi.org/10.1016/S0140-6736(04)15692-4 DOI: https://doi.org/10.1016/S0140-6736(04)15692-4

Hacke W, Kaste M, Fieschi C, Toni D, Lesaffre E, Von Kummer R, et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: the European Cooperative Acute Stroke Study (ECASS). JAMA 1995; 274: 1017–1025. DOI: https://doi.org/10.1001/jama.274.13.1017

https://doi.org/10.1001/JAMA.1995.03530130023023 DOI: https://doi.org/10.1001/jama.1995.03530130023023

Ma H, Campbell BCV, Parsons M, Churilov L, Levi C. Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke. N Engl J Med 2021; 384: 1278.

https://doi.org/10.1056/nejmx200014 DOI: https://doi.org/10.1056/NEJMx200014

Jørgensen HS, Kammersgaard LP, Houth J, Nakayama H, Raaschou HO, Larsen K, et al. Who benefits from treatment and rehabilitation in a stroke unit? A community-based study. Stroke 2000; 31: 434–439.

https://doi.org/10.1161/01.STR.31.2.434 DOI: https://doi.org/10.1161/01.STR.31.2.434

Langhorne P, Duncan P. Does the organization of postacute stroke care really matter? Stroke 2001; 32: 268–274.

https://doi.org/10.1161/01.STR.32.1.268 DOI: https://doi.org/10.1161/01.STR.32.1.268

Jørgensen HS, Reith J, Nakayama H, Kammersgaard LP, Raaschou HO, Olsen TS. What determines good recovery in patients with the most severe strokes? The Copenhagen stroke study. Stroke 1999; 30: 2008–2012.

https://doi.org/10.1161/01.STR.30.10.2008 DOI: https://doi.org/10.1161/01.STR.30.10.2008

Legg L. Rehabilitation therapy services for stroke patients living at home: systematic review of random-ised trials. Lancet 2004; 363: 352–356.

https://doi.org/10.1016/S0140-6736(04)15434-2 DOI: https://doi.org/10.1016/S0140-6736(04)15434-2

Outpatient Service Trialists. Therapy-based rehabilitation services for stroke patients at home. Cochrane Database Syst Rev 2003; 2003: CD002925.

https://doi.org/10.1002/14651858.CD002925 DOI: https://doi.org/10.1002/14651858.CD002925

Working group set up by the Finnish Medical Society Duodecim and the Finnish Neurologic Society. Stroke and transient ischemic attack. Current Care Guidelines.. The Finnish Medical Society Duodec-im; 2020. Available from: www.kaypahoito.fi

Meretoja A, Roine RO, Kaste M, Linna M, Roine S, Juntunen M, et al. Effectiveness of primary and com-prehensive stroke centers. Stroke 2010; 41: 1102–1107.

https://doi.org/10.1161/STROKEAHA.109.577718 DOI: https://doi.org/10.1161/STROKEAHA.109.577718

Takala T, Peurala SH, Erilä T, Huusko T, Viljanen T, Ylinen A, et al. Significant variation in stroke rehabilita-tion services in Finland. Lääkärilehti 2010; 65: 399–405. Available from: https://www-laakarilehti-fi.libproxy.helsinki.fi/tieteessa/terveydenhuoltoartikkelit/aivoverenkiertohairion-alkuvaiheen-kuntoutuksessa-suuria-vaihteluja-selvitys-avh-n-sairastaneiden-kuntoutuspalveluista-suomessa/

Koskinen M. The rehabilitation of stroke patients in Finland 2013–2015. Turku; 2016. Available from: https://dyajetwym1cg9.cloudfront.net/assets/files/4854/avh-kuntoutuksen_seurantatutkimuksen_loppuraportti.pdf

Kõrv J, Antsov K, Gross-Paju K, Kalju I, Kreis A, Liigant A, et al. Developments in quality of stroke care in Estonia. Eur Stroke J 2023; 8: 35–43.

https://doi.org/10.1177/23969873221110745 DOI: https://doi.org/10.1177/23969873221110745

Stevens E, Emmett E, Wang Y, McKevitt C, Wolfe C DA. The burden of stroke in Europe Report. King’s College London for the Stroke Alliance for Europe. Brussels; 2020. Available from: https://strokeeurope.eu/report-info/

Malmivaara A, Zampolini M, Stam H, Gutenbrunner C. Pros and cons of randomized controlled trials and benchmarking controlled trials in rehabilitation: an academic debate within the European Acad-emy of Rehabilitation Medicine. J Rehabil Med 2022; 54: jrm00319.

https://doi.org/10.2340/jrm.v54.2511 DOI: https://doi.org/10.2340/jrm.v54.2511

Häkkinen U. The PERFECT project: measuring performance of health care episodes. Ann Med 2011; 43: S1–S3.

https://doi.org/10.3109/07853890.2011.586901 DOI: https://doi.org/10.3109/07853890.2011.586901

Theofanidis D, Gibbon B. Nursing interventions in stroke care delivery: an evidence-based clinical re-view. J Vasc Nurs 2016; 34: 144–151.

https://doi.org/10.1016/j.jvn.2016.07.001 DOI: https://doi.org/10.1016/j.jvn.2016.07.001

Häkkinen U, Sund R. What works? The association of organisational structure, reforms and interven-tions on efficiency in treating hip fractures. Soc Sci Med 2021; 274: 113611.

https://doi.org/10.1016/J.SOCSCIMED.2020.113611 DOI: https://doi.org/10.1016/j.socscimed.2020.113611

Häkkinen U, Goude F, Hagen TP, Kruse M, Moger T, Peltola M, et al. A performance comparison of patient pathways in Nordic capital areas: a pilot study for ischaemic stroke patients. Scand J Public Health 2020; 48: 275–288.

https://doi.org/10.1177/1403494819863523 DOI: https://doi.org/10.1177/1403494819863523

Meretoja A, Kaste M, Roine RO, Juntunen M, Linna M, Hillbom M, et al. Trends in treatment and outcome of stroke patients in Finland from 1999 to 2007. PERFECT Stroke, a nationwide register study. Ann Med 201; 43: S22–30.

https://doi.org/10.3109/07853890.2011.586361 DOI: https://doi.org/10.3109/07853890.2011.586361

Malmivaara A, Meretoja A, Peltola M, Numerato D, Heijink R, Engelfriet P, et al. Comparing ischaemic stroke in six European countries. The EuroHOPE register study. Eur J Neurol 2015; 22: 284–291.

https://doi.org/10.1111/ENE.12560 DOI: https://doi.org/10.1111/ene.12560

Malmivaara A. System impact research: increasing public health and health care system performance. Ann Med 2016; 48: 211–215.

https://doi.org/10.3109/07853890.2016.1155228 DOI: https://doi.org/10.3109/07853890.2016.1155228

Peltola M, Juntunen M, Häkkinen U, Rosenqvist G, Seppälä TT, Sund R. A methodological approach for register-based evaluation of cost and outcomes in health care. Ann Med 2011; 43: S4–13.

https://doi.org/10.3109/07853890.2011.586364 DOI: https://doi.org/10.3109/07853890.2011.586364

Leppälä JM, Virtamo J, Heinonen OP. Validation of stroke diagnosis in the National Hospital Discharge Register and the Register of Causes of Death in Finland. Eur J Epidemiol 1999; 15: 155–160. DOI: https://doi.org/10.1023/A:1007504310431

https://doi.org/10.1023/A:1007504310431/METRICS

Groupers & Definition Tables – Nordic Casemix Centre. [cited 2024 Sep 7]. Available from: https://nordcase.org/products/groupers-definition-tables/

Mäklin S, Kokko P. Health and social care unit costs in Finland 2017. Terveyden ja hyvinvoinnin laitos (Institute Health Welfare) 2021 [cited 2024 Sep 7]. Available from: https://www.julkari.fi/handle/10024/142882

Häkkinen U, Hagen TP, Moger TA. Performance comparison of hip fracture pathways in two capital ci-ties: associations with level and change of integration.

https://doi.org/10.5617/njhe.4836 DOI: https://doi.org/10.5617/njhe.4836

Lechner M. The estimation of causal effects by difference-in-difference methods. Found Trends® Eco-nom 2011; 4: 165–224.

https://doi.org/10.1561/0800000014 DOI: https://doi.org/10.1561/0800000014

Villa JM. diff: Simplifying the estimation of difference-in-differences treatment effects. Stata J 2016; 16: 52–71. DOI: https://doi.org/10.1177/1536867X1601600108

Fonarow GC, Alberts MJ, Broderick JP, Jauch EC, Kleindorfer DO, Saver JL, et al. Stroke outcomes measures must be appropriately risk adjusted to ensure quality care of patients: a presidential advi-sory from the American Heart Association/American Stroke Association. Stroke 2014; 45: 1589–1601.

https://doi.org/10.1161/STR.0000000000000014 DOI: https://doi.org/10.1161/STR.0000000000000014

Pożarowszczyk N, Kurkowska-Jastrzębska I, Sarzyńska-Długosz I, Nowak M, Karliński M. Reliability of the modified Rankin Scale in clinical practice of stroke units and rehabilitation wards. Front Neurol 2023; 14: 1064642.

https://doi.org/10.3389/FNEUR.2023.1064642 DOI: https://doi.org/10.3389/fneur.2023.1064642

Additional Files

Published

2024-11-13

How to Cite

Korpi, N., Mikkelsson, M., Häkkinen, U., & Malmivaara, A. (2024). The effectiveness and costs of intensive stroke rehabilitation and improvements in patient pathway in Finland: a retrospective benchmarking controlled trial. Journal of Rehabilitation Medicine, 56, jrm34944. https://doi.org/10.2340/jrm.v56.34944

Issue

Section

Original Report

Categories