The Pericapsular Nerve Group (PENG) block in physical and rehabilitation medicine: an opinion paper
DOI:
https://doi.org/10.2340/jrm.v58.46559Keywords:
PENG block, Hip denervation, PhenolDownloads
References
Girón-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) block for hip fracture. Reg Anesth Pain Med 2018; 43: 859–863. DOI: https://doi.org/10.1097/AAP.0000000000000847
Girón-Arango L, Peng P. Pericapsular nerve group (PENG) block: what have we learned in the last 5 years? Reg Anesth Pain Med 2025; 50: 402–409. DOI: https://doi.org/10.1136/rapm-2024-105427
Staikou C, Rekatsina M, Leoni MLG, Chamos C, Kapsokalyvas I, Varrassi G, et al. Efficacy and safety of Pericapsular Nerve Group block (PENG) in hip surgery under general anaesthesia: a systematic literature review and meta-analysis. J Clin Med 2025; 14: 468. DOI: https://doi.org/10.3390/jcm14020468
Foussat E, Geffrier A, Guignans C, Ropars M, Butet S, Bonan I. Pericapsular hip chemical denervation with phenol: a case report suggesting the interest of this new tool in rehabilitation medicine. Ann Phys Rehabil Med 2025; 68: 101982. DOI: https://doi.org/10.1016/j.rehab.2025.101982
French ZP, Torres RV, Whitney DG. Elevated prevalence of osteoarthritis among adults with cerebral palsy. J Rehabil Med 2019; 51: 575–581. DOI: https://doi.org/10.2340/16501977-2582
GBD 2021 Osteoarthritis Collaborators. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Rheumatol 2023; 5: e508–e522.
O’Driscoll CS, Hughes AJ, Davey MS, Queally JM, O’Daly BJ. Total hip arthroplasty in patients with neurological conditions: a systematic review. Arthroplast Today 2022; 19: 101068. DOI: https://doi.org/10.1016/j.artd.2022.11.001
Tomlinson J, Ondruschka B, Prietzel T, Zwirner J, Hammer N. A systematic review and meta-analysis of the hip capsule innervation and its clinical implications. Sci Rep 2021; 11: 5299. DOI: https://doi.org/10.1038/s41598-021-84345-z
Gerhardt M, Johnson K, Atkinson R, Snow B, Shaw C, Brown A, et al. Characterisation and classification of the neural anatomy in the human hip joint. Hip Int 2012; 22: 75–81. DOI: https://doi.org/10.5301/HIP.2012.9042
Laumonerie P, Dalmas Y, Tibbo ME, Robert S, Durant T, Caste T, et al. Sensory innervation of the hip joint and referred pain: a systematic review of the literature. Pain Med 2021; 22: 1149–1157. DOI: https://doi.org/10.1093/pm/pnab061
Nielsen TD, Moriggl B, Søballe K, Kolsen-Petersen JA, Børglum J, Bendtsen TF. A Cadaveric study of ultrasound-guided subpectineal injectate spread around the obturator nerve and its hip articular branches. Reg Anesth Pain Med 2017; 42: 357–361. DOI: https://doi.org/10.1097/AAP.0000000000000587
Short AJ, Barnett JJG, Gofeld M, Baig E, Lam K, Agur AMR, et al. Anatomic study of innervation of the anterior hip capsule: implication for image-guided intervention. Reg Anesth Pain Med 2018; 43: 186–192. DOI: https://doi.org/10.1097/AAP.0000000000000778
Duan L, Li J, Chen Z, Wen T, He J, Zhang A. Posterior Hip Pericapsular Block (PHPB) with pericapsular nerve group (PENG) block for hip fracture: a case series. BMC Anesthesiol 2024; 24: 352. DOI: https://doi.org/10.1186/s12871-024-02731-2
Curatolo M. Central sensitization and pain: pathophysiologic and clinical insights. Curr Neuropharmacol 2024; 22: 15–22. DOI: https://doi.org/10.2174/1570159X20666221012112725
Kose SG, Kose HC, Celikel F, Tulgar S, Akkaya OT. Ultrasound-guided PENG block versus intraarticular corticosteroid injection in hip osteoarthritis: a randomised controlled study. Korean J Pain 2023; 36: 195–207. DOI: https://doi.org/10.3344/kjp.22325
Tran J, Agur A, Peng P. Is pericapsular nerve group (PENG) block a true pericapsular block? Reg Anesth Pain Med 2019. DOI: https://doi.org/10.1136/rapm-2018-100278
Wu H, Yang R-Z, Chen Y, Chen T, Qiu LC, Wu XD. The effect of pericapsular nerve group (PENG) block on postoperative analgesia in elderly patients who underwent proximal femoral nail anti-rotation surgery: a prospective, randomized-controlled trial. BMC Anesthesiol 2024; 24: 421. DOI: https://doi.org/10.1186/s12871-024-02805-1
Reysner M, Reysner T, Kowalski G, Mularski A, Daroszewski P, Wieczorowska-Tobis K. Chemical ablation of pericapsular nerve group with 95% ethanol for pain relief and quality of life in patients with hip osteoarthritis: a prospective, double-blinded, randomised, controlled trial. Br J Anaesth 2025; 135: 382–389. DOI: https://doi.org/10.1016/j.bja.2025.04.045
Alomari A, Kanjanapanang N, Peng P, Mittal N. Image-guided alcohol neurolysis for treatment of chronic hip pain secondary to avascular necrosis. Reg Anesth Pain Med 2026; 51: 823–826. DOI: https://doi.org/10.1136/rapm-2025-106915
Schaumburg HH, Byck R, Weller RO. The effect of phenol on peripheral nerve: a histological and electrophysiological study. J Neuropathol Exp Neurol 1970; 29: 615–630. DOI: https://doi.org/10.1097/00005072-197010000-00007
Zafonte RD, Munin MC. Phenol and alcohol blocks for the treatment of spasticity. Phys Med Rehabil Clin N Am 2001; 12: 817–832. DOI: https://doi.org/10.1016/S1047-9651(18)30034-2
Sasaki S, Chan WS, Ng TKT, Sham P. Ultrasound-guided pericapsular hip joint alcohol neurolysis for the treatment of hip pain: a case report of a novel approach. A A Pract 2018; 11: 60–62. DOI: https://doi.org/10.1213/XAA.0000000000000732
Rocha Romero A, Carvajal Valdy G, Lemus AJ. Ultrasound-guided pericapsular nerve group (PENG) hip joint phenol neurolysis for palliative pain. Can J Anaesth 2019; 66: 1270–1271. DOI: https://doi.org/10.1007/s12630-019-01448-y
Pressler MP, Renwick C, Lawson A, Singla P, Wahezi SE, Kohan LR. Radiofrequency ablation of the hip: review. Ann Palliat Med 2024; 13: 927–937. DOI: https://doi.org/10.21037/apm-23-470
Wit PR de, Beek R van, Schokker M, Wensing C, Hollmann MW, Kallewaard JW, et al. Genicular nerve radiofrequency ablation, phenol neurolysis or conservative medical management in patients with knee osteoarthritis: protocol for the RADIOPHENOL randomised controlled multicentre trial with three parallel groups. BMJ Open 2025; 15: e094576. DOI: https://doi.org/10.1136/bmjopen-2024-094576
Genêt F, Denormandie P, Keenan MA. Orthopaedic surgery for patients with central nervous system lesions: concepts and techniques. Ann Phys Rehabil Med 2019; 62: 225–233. DOI: https://doi.org/10.1016/j.rehab.2018.09.004
Rougereau G, Hollier-Larousse B, Bauer T, Genêt F, Salga M, Cale F. Anterior-approach total hip arthroplasty in patients with poliomyelitis: long-term outcomes. Orthop Traumatol Surg Res 2024; 110: 103964. DOI: https://doi.org/10.1016/j.otsr.2024.103964
David R, Hashemi M, Schatz L, Winston P. Multisite treatment with percutaneous cryoneurolysis for the upper and lower limb in long-standing post-stroke spasticity. Eur J Phys Rehabil Med 2024; 60: 793–797. DOI: https://doi.org/10.23736/S1973-9087.24.08346-1
Tay MRJ, Mittal N, Yao S, Farag J. Chemical neurolysis of genicular nerves for chronic non-cancer knee pain: a scoping review. Pain Med 2025; 26: 76–89. DOI: https://doi.org/10.1093/pm/pnae109
Downloads
Published
How to Cite
License
Copyright (c) 2026 Simon Butet, François Genet, Charles Guignans, Antoine Geffrier, Isabelle Bonan
This work is licensed under a Creative Commons Attribution 4.0 International License.
All digitalized JRM contents is available freely online. The Foundation for Rehabilitation Medicine owns the copyright for all material published until volume 40 (2008), as from volume 41 (2009) authors retain copyright to their work and as from volume 49 (2017) the journal has been published Open Access, under CC-BY-NC licences (unless otherwise specified). The CC-BY-NC licenses allow third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
From 2024, articles are published under the CC-BY licence. This license permits sharing, adapting, and using the material for any purpose, including commercial use, with the condition of providing full attribution to the original publication.
