Elevated colchicine sensitivity of dermal lymphocytes in mycosis fungoides

Authors

  • W. Sterry
  • GK. Steigleder
  • B. Nikolai

DOI:

https://doi.org/10.2340/0001555560257259

Abstract

Lymphocytes in chronic lymphocytic leukaemia and in other malignant lymphomas exhibit an extreme sensitivity to colchicine and are cytolysed in vitro by 10(-6) M colchicine. This characteristic can be quantified with the colchicine sensitivity index which is used for diagnostic purposes. We have demonstrated that lymphocytes liberated from skin infiltrates in mycosis fungoides (6 patients) show an elevated colchicine sensitivity of 44 (p < 0.01)

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Published

1980-05-05

How to Cite

Sterry, W., Steigleder, G., & Nikolai, B. (1980). Elevated colchicine sensitivity of dermal lymphocytes in mycosis fungoides. Acta Dermato-Venereologica, 60(3), 257–259. https://doi.org/10.2340/0001555560257259

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Section

Articles