Publishing Ethics

When reporting studies on human subjects all authors are required to follow the ICMJE requirements on privacy and informed consent. Information that could be used to identify patients, in the form of written descriptions, photographs, and pedigrees, should not be published unless it is essential for scientific purposes and the patient (or parent or guardian) gives written informed consent for publication. Informed consent for this purpose requires that the patient be shown the manuscript to be published. Where someone is deceased, please ensure you have written consent from the family or estate.

Clinical trials and studies involving animal experiments must be approved by a local ethics committee. Trial registration numbers should be included, and full details in the Material and Methods section.

Studies involving animal experiments must state that their care was in accordance with the institution's or national research council's guidelines for, or any national law on the care and use of laboratory animals. All animal work must have been conducted according to relevant national and international guidelines. Animal experimental procedure should be made as humane as possible and the details of anaesthetics and analgesics used should be clearly stated.

In order to improve the quality of randomised trials we have adapted to the CONSORT statement.