Use of in vitro epidermal cell cultures to study growth mechanisms in hyperplastic skin disorders
DOI:
https://doi.org/10.2340/00015555922224Abstract
Both atopic dermatitis and psoriasis are proliferative skin disordcrs that are self-limited, show hereditary tendencies and are postulated to result from changes in the cyclic AMP-beta adrenergic system of the epidermis. Cyclic nucleotides, polyamines, arachidonic acid and its metabolites, and several drugs are associated with changes in the hyperproliferative epidermis. These biologically active compounds have been shown to affect the in vitro function of both neonatal and adult human primary culture systems. These in vitro model systems can be used to study the growth mechanisms of hyperplastic skin disorders.Downloads
Download data is not yet available.
Downloads
Published
1980-11-11
How to Cite
Marcelo, C. L., & Voorhees, J. J. (1980). Use of in vitro epidermal cell cultures to study growth mechanisms in hyperplastic skin disorders. Acta Dermato-Venereologica, 60(92), 22–24. https://doi.org/10.2340/00015555922224
Issue
Section
Articles
License
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
