1,2-Ethanedithiol-induced erythema multiforme-like contact dermatitis

Authors

  • Chu CY Tjiu JW

DOI:

https://doi.org/10.1080/00015550410033571

Abstract

Contact dermatitis simulating erythema multiforme can be caused by many allergens. The chemical agent 1,2-ethanedithiol, which serves as a protective group in chemical synthesis, has hitherto only been implicated as an irritant. We report on a 22-year-old female chemistry student who developed widespread erythema multiforme-like lesions after local contact with 1,2-ethanedithiol. Many target lesions were observed bilaterally on her hands, forearms, arms, and on her forehead. One such lesion was histologically compatible with erythema multiforme. The patient had a positive patch test to 1,2-ethanedithiol, whereas none of 30 healthy subjects showed a positive reaction. However, eight of the 30 controls (26.7%) developed irritant reactions to 1,2-ethanedithiol. Cautious handling of the compound is a prudent precaution.

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Published

2004-09-17

How to Cite

Tjiu JW, C. C. (2004). 1,2-Ethanedithiol-induced erythema multiforme-like contact dermatitis. Acta Dermato-Venereologica, 84(5), 393–396. https://doi.org/10.1080/00015550410033571

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Articles