Tandem application of sodium lauryl sulfate and n-propanol does not lead to enhancement of cumulative skin irritation
DOI:
https://doi.org/10.1080/000155501317208327Abstract
Irritant contact dermatitis has a broad spectrum of clinical features and is a leading cause of occupational disease worldwide. It has been shown previously that a combination of chemically different irritants may cause an additive effect compared to single application of these substances. In this study, tandem application of sodium lauryl sulfate and n-propanol was investigated in 20 human volunteers using non-invasive bioengineering methods, such as measurement of transepidermal water loss and chromametry. N-propanol did not enhance cumulative skin irritation when used with sodium lauryl sulfate, as has been reported for toluene. As n-propanol is the active ingredient in many disinfectants, this is of particular interest regarding occupational skin irritation in health care workers.Downloads
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Published
2001-11-20
How to Cite
Kappes, U. P., Göritz, N., Wigger-Alberti, W., Heinemann, C., & Elsner, P. (2001). Tandem application of sodium lauryl sulfate and n-propanol does not lead to enhancement of cumulative skin irritation. Acta Dermato-Venereologica, 81(6), 403–405. https://doi.org/10.1080/000155501317208327
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