Histopathological and bacteriological findings in prurigo nodularis.
DOI:
https://doi.org/10.2340/0001555577049051Abstract
Prurigo nodularis is a chronic disease with unknown aetiology. Biopsy specimens of 43 patients with prurigo nodularis were taken for histopathological and mycobacteriological analyses. By conventional histopathology, 25 (58%) samples, and by immunostaining for S100 protein, 31 (72%) samples had changes relevant to prurigo nodularis. Twelve (28%) of the samples were positive for acid fast bacilli in tissue staining by Ziehl-Neelsen technique, including 4 of the 6 samples also positive for mycobacteria in cultivation. The results verified the usefulness of S100 staining in detection of neural hyperplasia in dermal nerves, a feature regarded as diagnostic for prurigo nodularis. They also indicated that atypical mycobacteria may be a contributing factor in prurigo nodularis.Downloads
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Published
1997-01-01
How to Cite
Mattila, J., Vornanen, M., & Katila, M. (1997). Histopathological and bacteriological findings in prurigo nodularis. Acta Dermato-Venereologica, 77(1), 49–51. https://doi.org/10.2340/0001555577049051
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