Two-point discrimination of itch in patients with atopic dermatitis and healthy subjects.
DOI:
https://doi.org/10.2340/00015555764851Abstract
The ability to perceive two pruritic stimuli as separate depending on the distance between them (two-point discrimination of itch) was determined in a single-blind study of 20 patients with atopic dermatitis and 20 healthy subjects. Itch was induced with pairs of histamine injections (0.1 micrograms each) given on the upper arm, either along its axis (longitudinally within a dermatome) or at right angles to it (transversally involving more than one dermatome). The interinjection distances were varied in 3-cm steps until the shortest distance at which the two itching stimuli could be perceived as separate was found. Pairs consisting of one injection of histamine (0.1 micrograms) and one of saline served as controls. The two-point discrimination of itch was significantly better in the atopic dermatitis patients than in the healthy controls, both longitudinally (atopic dermatitis: median 12 cm, range 3-21 cmDownloads
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Published
1996-01-01
How to Cite
Wahlgren, C., & Ekblom, A. (1996). Two-point discrimination of itch in patients with atopic dermatitis and healthy subjects. Acta Dermato-Venereologica, 76(1), 48–51. https://doi.org/10.2340/00015555764851
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