Malignant aneuploid spindle/cell transformation in a proliferating trichilemmal tumour.
DOI:
https://doi.org/10.2340/0001555573444446Abstract
A case of spindle/cell carcinoma developed on a proliferating trichilemmal tumour (PTT) is presented. The tumour on the scalp of an 84/year/old white woman was excised and histological examination showed typical features of PTT, but with a coexistent malignant spindle/cell tumour with a sarcomatoid appearance. There were some areas of transition between squamous trichilemmal epithelium and the neoplastic mass composed of atypical spindle/shaped cells. Two years later, the patient was well, and neither recurrence nor metastases were observed. We report the second case of PTT with a malignant spindle/cell transformation with a sarcomatoid appearance (spindle/cell carcinoma), and a proven aneuploidy, demonstrated with DNA/flow cytometric analysis.Downloads
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