Skin sensitization to cinnamic alcohol: the role of skin metabolism.
DOI:
https://doi.org/10.2340/0001555572264265Abstract
Cinnamic alcohol and cinnamic aldehyde are a cause of allergic contact dermatitis in man and give rise to similar rates of positive reactions in routine patch testing. However, data from animal models indicates that the aldehyde is the stronger sensitizer of the two. Circumstantial evidence has pointed to the conversion of alcohol to aldehyde in skin as the cause of cinnamic alcohol sensitization. This report discusses the subject in the light of studies of skin metabolism of cinnamic alcohol. Evidence of limited cross reactivity between cinnamic alcohol and cinnamic aldehyde is supported by data showing conversion of cinnamic alcohol to cinnamic aldehyde by an epidermal enzyme.Downloads
Download data is not yet available.
Downloads
Published
1992-08-01
How to Cite
Basketter, D. A. (1992). Skin sensitization to cinnamic alcohol: the role of skin metabolism. Acta Dermato-Venereologica, 72(4), 264–265. https://doi.org/10.2340/0001555572264265
Issue
Section
Articles
License
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
