Secretion of urokinase and tissue-plasminogen activator by epidermal cells in the presence of psoriatic fibroblast-conditioned medium.

Authors

  • Y Horiuchi
  • J M Marshall
  • S A Cederholm-Williams
  • T J Ryan

DOI:

https://doi.org/10.2340/0001555572401402

Abstract

The present study examined secretion of urokinase and tissue-plasminogen activator by epidermal cells in the presence of psoriatic or uninvolved skin fibroblast-conditioned medium. Using zymographic analyses, a 54kD lysis band and a small 110kD band derived from urokinase could be detected in the harvest fluid from keratinocytes treated with both psoriatic and uninvolved fibroblast-conditioned medium, as well as very weak lysis bands of 63kD and 120kD derived from tissue-plasminogen activator in the harvest fluid treated with psoriatic fibroblast-conditioned medium, but not with uninvolved fibroblast-conditioned medium.

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Published

1992-11-01

How to Cite

Horiuchi, Y., Marshall, J. M., Cederholm-Williams, S. A., & Ryan, T. J. (1992). Secretion of urokinase and tissue-plasminogen activator by epidermal cells in the presence of psoriatic fibroblast-conditioned medium. Acta Dermato-Venereologica, 72(6), 401–402. https://doi.org/10.2340/0001555572401402

Issue

Section

Articles