Epidermal transglutaminase in the ichthyoses.
DOI:
https://doi.org/10.2340/0001555571173175Abstract
Membrane-bound transglutaminase (TGm) is responsible for the cross-linking of proteins to form the cornified envelope. Since abnormalities have been reported in the envelope in certain ichthyoses, we have carried out a survey of TGm concentrations in scales from these disorders. Surprisingly, a striking and specific increase in enzyme activity was found in patients with non-erythrodermic autosomal recessive lamellar ichthyosis. It is not clear how this increase is related to the underlying recessive mutation.Downloads
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Published
1991-01-01
How to Cite
van Hooijdonk, C. A., Steijlen, P. M., Bergers, M., Mier, P. D., Traupe, H., & Happle, R. (1991). Epidermal transglutaminase in the ichthyoses. Acta Dermato-Venereologica, 71(2), 173–175. https://doi.org/10.2340/0001555571173175
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