Growth kinetics of fibroblasts from a patient with Ehlers-Danlos syndrome.

Authors

  • T Oku
  • F Nakayama
  • M Takigawa
  • K Inoue
  • M Yamada

DOI:

https://doi.org/10.2340/00015555705657

Abstract

A 6-year-old girl with Ehlers-Danlos syndrome (type I) who shows hyperelastic skin, hypermobile joints and delayed wound healing is reported. The growth kinetics of fibroblasts derived from her skin was examined using 3H-thymidine autoradiography. Our study showed that these fibroblasts had poor proliferative activity, compared with normal age-matched fibroblasts. Thus, we could suggest that the pathogenesis of Ehlers-Danlos syndrome was partially attributed to the lack of proliferative activity of the fibroblasts.

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Published

1990-01-01

How to Cite

Oku, T., Nakayama, F., Takigawa, M., Inoue, K., & Yamada, M. (1990). Growth kinetics of fibroblasts from a patient with Ehlers-Danlos syndrome. Acta Dermato-Venereologica, 70(1), 56–57. https://doi.org/10.2340/00015555705657

Issue

Section

Articles